Respiratory Health Inequities among Children and Young Adults with Cerebral Palsy in Aotearoa New Zealand: A Data Linkage Study.

IF 2.9 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Journal of Clinical Medicine Pub Date : 2022-11-25 DOI:10.3390/jcm11236968
Alexandra Sorhage, Samantha Keenan, Jimmy Chong, Cass Byrnes, Amanda Marie Blackmore, Anna Mackey, Timothy Hill, Dug Yeo Han, Ngaire Susan Stott
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Abstract

(1) Background: Respiratory disease is a leading cause of morbidity, mortality, and poor quality of life in children with cerebral palsy (CP). This study describes the prevalence of CP-related respiratory disease and the non-modifiable risk factors for respiratory-related hospital admissions in the Aotearoa New Zealand population. (2) Methods: New Zealand Cerebral Palsy Register (NZCPR) participant data and de-identified data from the National Minimum Dataset and Pharmaceutical Dispensing Collections were linked to identify all respiratory-related hospital admissions and respiratory illness-related antibiotic exposure over 5 years in individuals with CP (0−26 years). (3) Results: Risk factors for respiratory-related hospital admissions included being classified Gross Motor Function Classification System (GMFCS) IV or V compared to GMFCS I [OR = 4.37 (2.90−6.58), p < 0.0001; OR = 11.8 (7.69−18.10), p < 0.0001, respectively,]; having ≥2 antibiotics dispensed per year [OR = 4.42 (3.01−6.48), p < 0.0001]; and being of Māori ethnicity [OR = 1.47 (1.13−1.93), p < 0.0047]. Māori experienced health inequities compared to non-Māori, with greater functional disability, and also experienced greater antibiotic dispensing than the general population. (4) Conclusion: Māori children and young adults have a higher risk of respiratory-related illness. Priority should be given to the screening for potentially modifiable risk factors for all children with CP from diagnosis onwards in a way that ensures Māori health equity.

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新西兰奥特罗阿儿童和青年脑瘫患者的呼吸健康不平等:一项数据链接研究
(1)背景:呼吸系统疾病是脑瘫(CP)患儿发病率、死亡率和生活质量下降的主要原因。本研究描述了新西兰奥特罗阿人口中cp相关呼吸系统疾病的患病率和呼吸系统相关住院的不可改变的危险因素。(2)方法:将新西兰脑瘫登记(NZCPR)参与者数据和来自国家最低数据集和药品调剂收集的去识别数据相关联,以确定CP患者(0 - 26岁)5年内所有与呼吸相关的住院病例和与呼吸系统疾病相关的抗生素暴露。(3)结果:呼吸相关住院的危险因素包括:与GMFCS I相比,GMFCS IV或V级[or = 4.37(2.90−6.58),p < 0.0001;OR = 11.8(7.69−18.10),p < 0.0001,];每年使用≥2种抗生素[OR = 4.42(3.01−6.48),p < 0.0001];Māori种族[OR = 1.47 (1.13 ~ 1.93), p < 0.0047]。与non-Māori相比,Māori经历了更大的健康不平等,功能残疾更严重,并且比一般人群经历了更多的抗生素分配。(4)结论:Māori儿童和青壮年发生呼吸道相关疾病的风险较高。应优先考虑从诊断开始筛查所有CP儿童的潜在可改变的风险因素,以确保Māori健康公平。
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来源期刊
Journal of Clinical Medicine
Journal of Clinical Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
5.70
自引率
7.70%
发文量
6468
审稿时长
16.32 days
期刊介绍: Journal of Clinical Medicine (ISSN 2077-0383), is an international scientific open access journal, providing a platform for advances in health care/clinical practices, the study of direct observation of patients and general medical research. This multi-disciplinary journal is aimed at a wide audience of medical researchers and healthcare professionals. Unique features of this journal: manuscripts regarding original research and ideas will be particularly welcomed.JCM also accepts reviews, communications, and short notes. There is no limit to publication length: our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.
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