Surface modification of ureteral stents: development history, classification, function, and future developments.

IF 2.9 3区医学 Q3 ENGINEERING, BIOMEDICAL Expert Review of Medical Devices Pub Date : 2023-05-01 DOI:10.1080/17434440.2023.2198702

Kaiguo Xia, Xudong Shen, Xiaojie Ang, Bingbing Hou, Yang Chen, Kaiping Zhang, Zongyao Hao

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引用次数: 4

Abstract

Introduction: Ureteral stents are commonly used in urology but are frequently associated with hematuria, abdominal discomfort, urinary tract infection, stent displacement, and stent encrustation. Surface modification of ureteral stents is beneficial to solve the problem, and these can be divided into coated stents and drug-eluting stents according to the modification method. Coated stents can be divided into hydrophilic coatings, antibacterial coatings, and anti-encrustation coatings. Drug-eluting stents can be divided into antimicrobial drug-eluting, antispasmodic analgesic drug-eluting, anti-ureteral stricture drug-eluting, and anti-tumor drug-eluting. Surface modification of ureteral stents can not only reduce complications related to ureteral stents but also strengthen the treatment of certain urologic diseases, which has a high clinical application value.

Areas covered: This review focuses on highlighting and summarizing the latest research progress about surface modification of ureteral stents, ureteral stent development history, classification, functions, and future development prospects.

Expert opinion: The purpose of this article is to discuss surface modification of ureteral stents to reduce stent-related complications and potential research directions for the treatment of urinary tract tumors are also briefly discussed, to help guide further innovation in ureteral stent coatings, which contribute to the future progress of ureteral stents surface modification.

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输尿管支架表面修饰:发展历史、分类、功能及未来发展。

导读:输尿管支架是泌尿外科常用的支架，但常伴有血尿、腹部不适、尿路感染、支架移位和支架结痂。输尿管支架的表面修饰有利于解决这一问题，根据修饰方法可分为涂层支架和药物洗脱支架。涂层支架可分为亲水性涂层、抗菌涂层和防结痂涂层。药物洗脱支架可分为抗菌药物洗脱、抗痉挛镇痛药物洗脱、抗输尿管狭窄药物洗脱和抗肿瘤药物洗脱。输尿管支架表面修饰不仅可以减少与输尿管支架相关的并发症，而且可以加强对某些泌尿系统疾病的治疗，具有很高的临床应用价值。涵盖领域:重点介绍和总结输尿管支架表面修饰的最新研究进展，输尿管支架的发展历史、分类、功能及未来发展前景。专家意见:本文的目的是探讨输尿管支架表面修饰以减少支架相关并发症，并简要讨论治疗尿路肿瘤的潜在研究方向，以帮助指导输尿管支架涂层的进一步创新，为输尿管支架表面修饰的未来发展做出贡献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Medical Devices 医学-工程：生物医学

CiteScore

5.90

自引率

3.20%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal serves the device research community by providing a comprehensive body of high-quality information from leading experts, all subject to rigorous peer review. The Expert Review format is specially structured to optimize the value of the information to reader. Comprehensive coverage by each author in a key area of research or clinical practice is augmented by the following sections: Expert commentary - a personal view on the most effective or promising strategies Five-year view - a clear perspective of future prospects within a realistic timescale Key issues - an executive summary cutting to the author''s most critical points In addition to the Review program, each issue also features Medical Device Profiles - objective assessments of specific devices in development or clinical use to help inform clinical practice. There are also Perspectives - overviews highlighting areas of current debate and controversy, together with reports from the conference scene and invited Editorials.