[Autism Spectrum Disorders in Adulthood: Empirical Findings on Comorbidities, Differential Diagnoses, and the Clinical Utility of the AQ].

IF 1.1 4区医学 Q4 PSYCHIATRY Psychiatrische Praxis Pub Date : 2023-10-01 Epub Date: 2023-05-09 DOI:10.1055/a-2044-8540

Tanja Sappok, Mareike Bayer, Daria Tarasova, Heika Kaiser, Thomas Bergmann

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Abstract

AUTISM: spectrum disorders (ASD) often remain undiagnosed until adulthood. The aim of this study is to report differential diagnoses (DDX) and comorbidities of adults without intellectual impairment suspected of having an ASD and to test the self-assessment questionnaire Autism Quotient (AQ) for its suitability for screening.

Methods: DDX and comorbidities were recorded with standardized scales in an autism outpatient clinic in 106 individuals. The AQ was tested against the expert judgment of an interdisciplinary case conference using ROC analysis.

Results: Affective disorders were common in both groups (48%); other DDX were phobias (33%) and personality disorders (22%). The AQ showed an AUC of 0,527 with sensitivity/specificity of 70%/35%.

Conclusions: Adults suspected of having autism are highly burdened by DDX and comorbidities. An interdisciplinary diagnostic procedure based on standardized scales is useful, whereas the AQ hardly differentiates between persons with and without ASD.

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[成年期自闭症谱系障碍：合并症、鉴别诊断和AQ临床应用的经验发现]。

自闭症：谱系障碍（ASD）通常直到成年才被诊断出来。本研究的目的是报告疑似患有自闭症谱系障碍的无智力障碍成年人的鉴别诊断（DDX）和合并症，并测试自我评估问卷自闭症商（AQ）是否适合筛查。方法：采用标准量表对106名自闭症门诊患者的DDX和合并症进行记录。AQ是根据跨学科案例会议的专家判断使用ROC分析进行测试的。结果：两组患者情感障碍均较常见（48%）；其他DDX是恐惧症（33%）和人格障碍（22%）。AQ显示AUC为0527，敏感性/特异性为70%/35%。结论：怀疑患有自闭症的成年人对DDX和合并症的负担很重。基于标准化量表的跨学科诊断程序是有用的，而AQ很难区分ASD患者和非ASD患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychiatrische Praxis PSYCHIATRY-

CiteScore

3.90

自引率

9.10%

发文量

103

期刊介绍： Sozialpsychiatrisch orientiert Aktuelle Originalarbeiten und fundierte Übersichten Pro-Kontra-Debatten zu Brennpunktthemen Informative Fallbeispiele Vorstellung internationaler Studien