Survival Rates in Elderly Patients on Continuous Ambulatory Peritoneal Dialysis.

Bach Nguyen, Quynh Thi Huong Bui, Phuong Que Tran
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Abstract

Purpose: The present study aimed at evaluating the survival rate, its associated factors, and the causes of death in elderly patients undergoing continuous ambulatory peritoneal dialysis (CAPD) in Vietnam.

Patients and methods: This is a retrospective, observational study conducted among patients aged ≥65 years who underwent CAPD at Thong Nhat Hospital, Ho Chi Minh City, Vietnam, from April 2012 to December 2020. The Kaplan-Meier method was used to calculate the cumulative survival rate, and the Log rank test was used to analyze the factors associated with the survival rate of patients.

Results: This study enrolled a total of 68 patients with a mean age of 71.93 ± 7.44 years at the initiation of CAPD. The most common complication among kidney failure patients was diabetic nephropathy (39.71%). The rate of concomitant cardiovascular diseases was 58.82%. The average survival rate was 45.59 ± 4.01 months. Peritonitis was the most common factor causing death (31.25%), followed by cardiovascular diseases (28.12%) and malnutrition (25%). The factors that impacted the survival rate included concomitant cardiovascular diseases, low serum albumin (<35 g/dL), and an indication of CAPD due to exhausted vascular access for hemodialysis at baseline. The main factor associated with a shorter survival time was concomitant cardiovascular diseases.

Conclusion: It is necessary to improve the survival time beyond 5 years for elderly patients undergoing CAPD, especially for those with concomitant cardiovascular diseases. Besides the prevention of peritonitis, adequate measures to protect from cardiovascular diseases and malnutrition will reduce the mortality rate in patients on CAPD.

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老年患者持续非卧床腹膜透析的生存率。
目的:本研究旨在评估越南接受连续动态腹膜透析(CAPD)的老年患者的生存率、相关因素和死亡原因。患者和方法:这是一项回顾性观察性研究,研究对象为2012年4月至2020年12月在越南胡志明市通艺医院接受CAPD治疗的年龄≥65岁的患者。累积生存率采用Kaplan-Meier法计算,Log rank检验分析影响患者生存率的相关因素。结果:本研究共纳入68例患者,CAPD开始时的平均年龄为71.93±7.44岁。肾衰竭患者最常见的并发症是糖尿病肾病(39.71%)。合并心血管疾病的发生率为58.82%。平均生存率为45.59±4.01个月。最常见的死亡原因是腹膜炎(31.25%),其次是心血管疾病(28.12%)和营养不良(25%)。影响生存率的因素包括合并心血管疾病、血清白蛋白水平低(结论:老年CAPD患者,特别是合并心血管疾病的患者,有必要提高5年以上的生存时间。除了预防腹膜炎外,预防心血管疾病和营养不良的适当措施将降低CAPD患者的死亡率。
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来源期刊
CiteScore
3.90
自引率
5.00%
发文量
40
审稿时长
16 weeks
期刊介绍: International Journal of Nephrology and Renovascular Disease is an international, peer-reviewed, open-access journal focusing on the pathophysiology of the kidney and vascular supply. Epidemiology, screening, diagnosis, and treatment interventions are covered as well as basic science, biochemical and immunological studies. In particular, emphasis will be given to: -Chronic kidney disease- Complications of renovascular disease- Imaging techniques- Renal hypertension- Renal cancer- Treatment including pharmacological and transplantation- Dialysis and treatment of complications of dialysis and renal disease- Quality of Life- Patient satisfaction and preference- Health economic evaluations. The journal welcomes submitted papers covering original research, basic science, clinical studies, reviews & evaluations, guidelines, expert opinion and commentary, case reports and extended reports. The main focus of the journal will be to publish research and clinical results in humans but preclinical, animal and in vitro studies will be published where they shed light on disease processes and potential new therapies and interventions.
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