Forecasting ICU Census by Combining Time Series and Survival Models.

Lori L Murray, John G Wilson, Felipe F Rodrigues, Gregory S Zaric
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Abstract

Capacity planning of ICUs is essential for effective management of health safety, quality of patient care, and the allocation of ICU resources. Whereas ICU length of stay (LOS) may be estimated using patient information such as severity of illness scoring systems, ICU census is impacted by both patient LOS and arrival patterns. We set out to develop and evaluate an ICU census forecasting algorithm using the Multiple Organ Dysfunction Score (MODS) and the Nine Equivalents of Nursing Manpower Use Score (NEMS) for capacity planning purposes.

Design: Retrospective observational study.

Setting: We developed the algorithm using data from the Medical-Surgical ICU (MSICU) at University Hospital, London, Canada and validated using data from the Critical Care Trauma Centre (CCTC) at Victoria Hospital, London, Canada.

Patients: Adult patient admissions (7,434) to the MSICU and (9,075) to the CCTC from 2015 to 2021.

Interventions: None.

Measurements and main results: We developed an Autoregressive integrated moving average time series model that forecasts patients arriving in the ICU and a survival model using MODS, NEMS, and other factors to estimate patient LOS. The models were combined to create an algorithm that forecasts ICU census for planning horizons ranging from 1 to 7 days. We evaluated the algorithm quality using several fit metrics. The root mean squared error ranged from 2.055 to 2.890 beds/d and the mean absolute percentage error from 9.4% to 13.2%. We show that this forecasting algorithm provides a better fit when compared with a moving average or a time series model that directly forecasts ICU census. Additionally, we evaluated the performance of the algorithm using data during the global COVID-19 pandemic and found that the error of the forecasts increased proportionally with the number of COVID-19 patients in the ICU.

Conclusions: It is possible to develop accurate tools to forecast ICU census. This type of algorithm may be important to clinicians and managers when planning ICU capacity as well as staffing and surgical demand planning over a short time horizon.

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结合时间序列和生存模型预测ICU人口普查。
ICU的能力规划对于有效管理健康安全、患者护理质量和ICU资源分配至关重要。虽然ICU住院时间(LOS)可以使用患者信息(如疾病严重程度评分系统)来估计,但ICU人口普查受到患者住院时间和到达模式的影响。我们着手开发和评估一种ICU人口普查预测算法,该算法使用多器官功能障碍评分(MODS)和九等量护理人力使用评分(NEMS)进行容量规划。设计:回顾性观察性研究。环境:我们使用来自加拿大伦敦大学医院内科外科ICU (MSICU)的数据开发算法,并使用来自加拿大伦敦维多利亚医院重症监护创伤中心(CCTC)的数据进行验证。患者:2015年至2021年,MSICU成年患者入院(7434例),CCTC成年患者入院(9075例)。干预措施:没有。测量和主要结果:我们开发了一个自回归综合移动平均时间序列模型来预测到达ICU的患者,以及一个使用MODS、NEMS和其他因素来估计患者LOS的生存模型。这些模型结合起来创建了一个算法,可以预测ICU人口普查的规划范围从1天到7天。我们使用几个拟合指标来评估算法的质量。均方根误差为2.055 ~ 2.890张/d,平均绝对百分比误差为9.4% ~ 13.2%。我们表明,与直接预测ICU人口普查的移动平均或时间序列模型相比,该预测算法提供了更好的拟合。此外,我们使用全球COVID-19大流行期间的数据评估了算法的性能,发现预测的误差随着ICU中COVID-19患者的数量成比例地增加。结论:开发准确预测ICU人口普查的工具是可行的。这种类型的算法对于临床医生和管理人员在短期内规划ICU容量以及人员配置和手术需求规划时可能很重要。
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