Changes in anabolic and catabolic activity among women taking part in an alternative labour market programme.

Hugo Westerlund, Anna Bergström, Töres Theorell
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引用次数: 6

Abstract

Thirty-two female participants in a mobilising labour market programme offering temporary, alternative employment in Sweden were followed longitudinally for one year, including a six month post participation follow-up period. It can be hypothesised that an important aspect of the physiological effects of unemployment is a change in the balance between anabolic and catabolic activities in the body and that re-employment should lead to a shift towards anabolism. An earlier study of a smaller subset of the data, however, including both men and women, showed increased prolactin and decreased dehydroepiadrosterone sulphate (DHEA-s) levels, contrary to the initial hypothesis. In the present analysis, intended to elucidate these results, psychophysiological data were summarised in two indices, one connected with anabolism (made up of testosterone and DHEA-s) and one with catabolism (prolactin, gamma-glutamyl transferase, aspartate amino transferase, alpha levuline amino transferase, and body mass index). In addition, self-rated anxiety, depression, hopelessness and personal control were analysed. The results indicate that the effect of 'better' activities within the programme was a temporary increase in anabolism, possibly indicating lower stress levels, and the effect of 'worse' activities, on the one hand, a temporary decrease in the catabolic index, probably reflecting repressed alcohol consumption, and, on the other hand, impaired anabolism. There was also a general but transient decrease in depressiveness measured by the Hospital Anxiety and Depression Scale. The results seem to imply that it is difficult to achieve lasting effects through a relatively short participation in a mobilising programme.

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参加替代劳动力市场方案的妇女的合成代谢和分解代谢活动的变化。
对瑞典提供临时替代就业的调动劳动力市场方案的32名女性参与者进行了为期一年的纵向跟踪调查,其中包括参与后六个月的后续期。可以假设,失业的生理影响的一个重要方面是改变体内合成代谢和分解代谢活动之间的平衡,再就业应该导致向合成代谢的转变。然而,对一小部分数据的早期研究(包括男性和女性)显示,催乳素增加,硫酸脱氢表雄酮(dhea - 5)水平下降,这与最初的假设相反。在本分析中,为了阐明这些结果,心理生理数据被总结为两个指标,一个与合成代谢(由睾酮和DHEA-s组成)和一个与分解代谢(催乳素、γ -谷氨酰转移酶、天冬氨酸氨基转移酶、α -乙酰丙氨酸氨基转移酶和体重指数)有关。此外,还分析了自评焦虑、抑郁、绝望和个人控制。结果表明,“较好”的活动对合成代谢的影响是暂时的增加,可能表明压力水平较低,而“较差”的活动的影响,一方面是分解代谢指数的暂时下降,可能反映了酒精消耗的抑制,另一方面是合成代谢的受损。通过医院焦虑和抑郁量表测量,抑郁症也有普遍但短暂的减少。结果似乎表明,通过相对短期的参与动员方案很难取得持久的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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