The Effects of Alcohol and Cannabis Co-Use on Neurocognitive Function, Brain Structure, and Brain Function.

IF 2.1 Q3 NEUROSCIENCES Current Behavioral Neuroscience Reports Pub Date : 2021-12-01 DOI:10.1007/s40473-021-00243-8

Margaret F Bedillion, Sara K Blaine, Eric D Claus, Emily B Ansell

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引用次数: 3

Abstract

Purpose of review: Given increases in the rates of alcohol and cannabis co-use among adolescents and young adults, this review aims to summarize literature on the effects of alcohol and cannabis co-use on neurocognitive functioning, brain structure, and brain function.

Recent findings: The limited existing studies examining concurrent, recent, and lifetime alcohol and cannabis co-use suggest effects on the brain are likely multifaceted. The majority of studies report that co-use is associated with negative outcomes such as impaired cognitive function and significant alterations in key structural and functional regions of the brain, while others report null effects of co-use compared to non-substance using control and single-substance use groups.

Summary: Current studies lack a general consensus on methodology, definitions of concurrent and simultaneous use, and neuroimaging approaches, which makes it challenging to draw strong conclusions about the effects of co-use. More studies are needed to explore the effects of co-use in the context of simultaneous alcohol and cannabis use.

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酒精和大麻共同使用对神经认知功能、脑结构和脑功能的影响。

综述目的:鉴于青少年和青壮年中酒精和大麻同时使用的比例有所增加，本综述旨在总结有关酒精和大麻同时使用对神经认知功能、脑结构和脑功能影响的文献。最近的发现:现有的有限研究调查了同时、最近和终生饮酒和大麻的共同使用，表明对大脑的影响可能是多方面的。大多数研究报告称，共同使用与认知功能受损和大脑关键结构和功能区域的重大改变等负面结果有关，而其他研究报告称，与不使用药物的对照组和单一药物使用组相比，共同使用药物没有任何影响。摘要:目前的研究在方法学、同时使用和同时使用的定义以及神经成像方法方面缺乏普遍共识，这使得对共同使用的效果得出强有力的结论具有挑战性。需要更多的研究来探讨在同时使用酒精和大麻的情况下共同使用的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Behavioral Neuroscience Reports Medicine-Public Health, Environmental and Occupational Health

CiteScore

3.60

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0.00%

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期刊介绍： Under the leadership of Emil Coccaro, Current Behavioral Neuroscience Reports will provide an in-depth review of topics covering personality and impulse control disorders, psychosis, mood and anxiety disorders, genetics and neuroscience, geropsychiatry and cognitive disorders of late life, child and developmental psychiatry, addictions, and neuromodulation.We accomplish this aim by inviting international authorities to contribute review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. By providing clear, insightful balanced contributions, the journal intends to serve those involved in the field of behavioral neuroscience.