Effect of Phacoemulsification on Intraocular Pressure in Eyes with Functioning Tube Shunts.

IF 1.6 Q3 OPHTHALMOLOGY Journal of Ophthalmic & Vision Research Pub Date : 2023-04-01 DOI:10.18502/jovr.v18i2.13180
Wesam Shamseldin Shalaby, Sonali Patel, Sophia S Lam, Allen Ganjei, Aakriti Garg Shukla, Natasha Kolomeyer, Daniel Lee, L Jay Katz, Marlene R Moster, Jonathan Myers, Reza Razeghinejad
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Abstract

Purpose: To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in eyes with functioning tube shunts.

Methods: This was a retrospective chart review of primary open-angle glaucoma (POAG) patients with a functioning tube who underwent phacoemulsification and had 24 months of follow-up. The primary end point was defined as surgical failure (IOP > 21 mmHg) at month 24, progression to no light perception (NLP) vision, glaucoma reoperation, or implant removal. Surgical failure defined as IOP >18 and >15 mmHg, changes in visual acuity (VA), IOP, and number of medications were assessed.

Results: Twenty-seven eyes of 27 patients with moderate or severe POAG were included. The mean age of the patients was 64.2 ± 10.8 years. The interval between the tube shunt and phacoemulsification was 28.8 ± 25.0 months. At the end of the study, four (14.8%) eyes met the failure criteria; the average time to failure was 9.3 ± 3.8 months. The causes of failure were high IOP in two (50.0%) and glaucoma reoperation in two (50.0%) eyes; however, no eyes progressed to NLP vision. Surgical failure defined as IOP >18 and >15 mmHg showed an increasing failure rate (18.5% and 48.5%, respectively).Themean IOP and medications number remained stable at month 24 compared to baseline (P = 0.131 and P = 0.302, respectively). Initially, VA showed improvement, with the greatest improvement at 6 months (P = 0.001), but at 24 months the improvement was no longer significant (P = 0.430).

Conclusion: Phacoemulsification in patients with functioning tubes did not change the mean IOP in most of the patients (86.2%); the number of medications also did not increase.

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超声乳化术对正常分流眼眼压的影响。
目的:探讨超声乳化术对正常分流眼眼压的影响。方法:回顾性分析原发开角型青光眼(POAG)患者行超声乳化术,随访≥24个月。主要终点定义为第24个月手术失败(IOP > 21 mmHg),进展为无光感(NLP)视力,青光眼再手术或植入物移除。手术失败定义为IOP >18和>15 mmHg,视力(VA)、IOP和药物数量的变化进行评估。结果:纳入27例中重度POAG患者27只眼。患者平均年龄64.2±10.8岁。输卵管分流至超声乳化手术的时间间隔为28.8±25.0个月。研究结束时,4只(14.8%)眼符合失效标准;平均失效时间为9.3±3.8个月。失败原因为高IOP 2例(50.0%),青光眼再手术2例(50.0%);然而,没有眼睛进展到NLP视力。手术失败定义为IOP >18和>15 mmHg,失败率增加(分别为18.5%和48.5%)。与基线相比,平均IOP和药物数量在第24个月保持稳定(P = 0.131和P = 0.302)。最初,VA表现出改善,在6个月时改善最大(P = 0.001),但在24个月时改善不再显著(P = 0.430)。结论:输卵管功能正常的患者行超声乳化术后,大多数患者(86.2%)的平均IOP未发生改变;药物的数量也没有增加。
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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
63
审稿时长
30 weeks
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