Determining the Optimal Dosage of Corticosteroid Injection in Trigger Finger.

IF 1.8 Q2 ORTHOPEDICS HAND Pub Date : 2024-10-01 Epub Date: 2023-05-16 DOI:10.1177/15589447231170326
Jared Bookman, Madeline Rocks, Karen Noh, Omri Ayalon, Jacques Hacquebord, Louis Catalano, Steven Glickel
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Abstract

Background: Corticosteroid injection is the mainstay of nonoperative treatment for trigger finger (stenosing tenosynovitis), but despite substantial experience with this treatment, there is minimal available evidence as to the optimal corticosteroid dosing. The purpose of this study is to compare the efficacy of 3 different injection dosages of triamcinolone acetonide for the treatment of trigger finger.

Methods: Patients diagnosed with a trigger finger were prospectively enrolled and treated with an initial triamcinolone acetonide (Kenalog) injection of 5 mg, 10 mg, or 20 mg. Patients were followed longitudinally over a 6-month period. Patients were assessed for duration of clinical response, clinical failure, Visual Analog Scale (VAS) pain scores, and Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) scores.

Results: A total of 146 patients (163 trigger fingers) were enrolled over a 26-month period. At 6-month follow-up, injections were still effective (without recurrence, secondary injection, or surgery) in 52% of the 5-mg group, 62% of the 10-mg group, and 79% of the 20-mg group. Visual Analog Scale at final follow-up improved by 2.2 in the 5-mg group, 2.7 in the 10-mg group, and 4.5 in the 20-mg group. The QuickDASH scores at final follow-up improved by 11.8 in the 5-mg group, 21.5 in the 10-mg group, and 28.9 in the 20-mg group.

Conclusions: Minimal evidence exists to guide the optimal dosing of steroid injection in trigger digits. When compared with 5-mg and 10-mg doses, a 20-mg dose was found to have a significantly higher rate of clinical effectiveness at 6-month follow-up. The VAS and QuickDASH scores were not significantly different between the 3 groups.

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确定皮质类固醇注射在扳机指中的最佳剂量
背景:皮质类固醇注射是扳机指(狭窄性腱鞘炎)非手术治疗的主要方法,但尽管这种治疗方法经验丰富,但关于皮质类固醇的最佳剂量却鲜有证据。本研究的目的是比较三种不同剂量的曲安奈德注射液治疗扳机指的疗效:方法:对确诊为扳机指的患者进行前瞻性登记,并首次注射 5 毫克、10 毫克或 20 毫克的曲安奈德(Kenalog)。对患者进行为期 6 个月的纵向随访。对患者的临床反应持续时间、临床失败、视觉模拟量表(VAS)疼痛评分以及手臂、肩部和手部快速残疾(QuickDASH)评分进行评估:共有 146 名患者(163 个扳机指)接受了为期 26 个月的治疗。在 6 个月的随访中,52% 的 5 毫克组、62% 的 10 毫克组和 79% 的 20 毫克组患者的注射仍然有效(无复发、二次注射或手术)。在最终随访中,5 毫克组的视觉模拟量表提高了 2.2,10 毫克组提高了 2.7,20 毫克组提高了 4.5。最终随访时,5 毫克组的 QuickDASH 评分提高了 11.8 分,10 毫克组提高了 21.5 分,20 毫克组提高了 28.9 分:结论:只有极少数证据可指导扳机指注射类固醇的最佳剂量。与 5 毫克和 10 毫克剂量相比,20 毫克剂量在 6 个月随访时的临床有效率明显更高。三组之间的 VAS 和 QuickDASH 评分无明显差异。
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来源期刊
HAND
HAND Medicine-Surgery
CiteScore
3.30
自引率
0.00%
发文量
209
期刊介绍: HAND is the official journal of the American Association for Hand Surgery and is a peer-reviewed journal featuring articles written by clinicians worldwide presenting current research and clinical work in the field of hand surgery. It features articles related to all aspects of hand and upper extremity surgery and the post operative care and rehabilitation of the hand.
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