Distribution of the follicular and luteal phase lengths and their age-dependent changes in Japanese women: A large population study.

IF 2.7 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Reproductive Medicine and Biology Pub Date : 2023-05-12 eCollection Date: 2023-01-01 DOI:10.1002/rmb2.12516
Sawa Mitake, Osamu Wada-Hiraike, Kosuke Kashiwabara, Akari Nakamura, Risa Nasu, Maaya Hine, Yutaka Matsuyama, Tomoyuki Fujii, Yutaka Osuga
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Abstract

Purpose: The current definition of menstrual cycle length in a Japanese woman is different from those of WHO definition, and the original data are outdated. We aimed to calculate the distribution of follicular and luteal phases length in modern Japanese women with various menstrual cycles.

Methods: This study determined the lengths of the follicular and luteal phases of Japanese women using basal body temperature data collected via a smartphone application from 2015 to 2019, and the data were analyzed using the Sensiplan method. Over 9 million temperature readings from more than 80 000 participants were analyzed.

Results: The mean duration of the low-temperature (follicular) phase averaged 17.1 days and was shorter among participants aged 40-49 years. The mean duration of the high-temperature (luteal) phase was 11.8 days. The variance and maximum-minimum difference of the length of the low temperature period were significant in women under 35 years old than women aged more than 35 years.

Conclusions: The shortening of the follicular phase in women aged 40-49 years implied a relationship with the rapid decline of ovarian reserve in these women, and the age 35 years old was turning point of ovulatory function.

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日本女性卵泡期和黄体期长度的分布及其随年龄的变化:一项大型人口研究。
目的:目前日本女性月经周期长度的定义与世界卫生组织的定义不同,原始数据已经过时。我们旨在计算不同月经周期的现代日本女性卵泡期和黄体期长度的分布情况:本研究利用从 2015 年至 2019 年通过智能手机应用程序收集的基础体温数据确定了日本女性的卵泡期和黄体期长度,并使用 Sensiplan 方法对数据进行了分析。分析了来自 8 万多名参与者的 900 多万个体温读数:低温期(卵泡期)的平均持续时间为 17.1 天,在 40-49 岁的参与者中持续时间较短。高温期(黄体期)的平均持续时间为 11.8 天。与 35 岁以上的女性相比,35 岁以下女性低温期长度的方差和最大-最小差异显著:结论:40-49 岁妇女的卵泡期缩短意味着这些妇女的卵巢储备功能迅速下降,而 35 岁是排卵功能的转折点。
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来源期刊
CiteScore
5.70
自引率
5.90%
发文量
53
审稿时长
20 weeks
期刊介绍: Reproductive Medicine and Biology (RMB) is the official English journal of the Japan Society for Reproductive Medicine, the Japan Society of Fertilization and Implantation, the Japan Society of Andrology, and publishes original research articles that report new findings or concepts in all aspects of reproductive phenomena in all kinds of mammals. Papers in any of the following fields will be considered: andrology, endocrinology, oncology, immunology, genetics, function of gonads and genital tracts, erectile dysfunction, gametogenesis, function of accessory sex organs, fertilization, embryogenesis, embryo manipulation, pregnancy, implantation, ontogenesis, infectious disease, contraception, etc.
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