Spectral parameters of gait differentiate diabetic patients from healthy individuals

Q2 Health Professions Foot Pub Date : 2023-09-01 DOI:10.1016/j.foot.2023.102038

Mario Inacio , Patrick Esser , Junxian Li , Lei Xu , Hui Zeng , Rui He , Helen Dawes , Fang Liu

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引用次数: 0

Abstract

Background

Diabetes mellitus (DM) is a clinical condition that affects gait performance and control in millions of individuals worldwide. Contrary to basic spatiotemporal parameters, gait-based spectral analysis may provide useful insights into gait neuromotor control. Hence, this study was set to investigate the spectral content of gait at the preferred speed in patients with DM.

Methods

Total 1117 individuals [658 DM and 649 healthy adults (HA)] performed a 10 m walk while wearing an inertial measurement unit over the fourth lumbar vertebra. Mann-Whitney-U test was used for between-group gait parameters comparisons.

Results

DM group had a slower step time (1.2%, p < 0.05) and gait speed (2.4%, p < 0.05) than HA. Additionally, DM individuals showed reduced dominant frequency (DM:0.24 Hz vs HA:0.25 Hz on average, p < 0.05). Increased antero-posterior and vertical dominant frequency width (DM:1.73 Hz vs HA:1.76 Hz on average, p < 0.05) and medio-lateral relative power spectral density at the dominant frequency (DM:6.19% vs HA:5.96%, p < 0.05).

Conclusions

It was demonstrated for the first time that the gait spectral content, not only corroborates spatiotemporal characteristics, but also provides further insight into their neuromotor control deficits in diabetic patients. Ultimately, this type of analysis in the diabetic population can help guide the therapeutic interventions to prevent diabetic foot.

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步态的光谱参数将糖尿病患者与健康人区分开来。

背景：糖尿病（DM）是一种影响全球数百万人步态表现和控制的临床疾病。与基本的时空参数相反，基于步态的频谱分析可以为步态神经运动控制提供有用的见解。因此，本研究旨在研究糖尿病患者在首选速度下步态的频谱含量。方法：总共1117名患者[658名糖尿病患者和649名健康成年人（HA）]在第四腰椎上佩戴惯性测量装置时进行了10米的步行。Mann--Whitney-U检验用于组间步态参数比较。结果：DM组的步进时间较慢（1.2%，p结论：首次证明步态频谱含量不仅证实了糖尿病患者的时空特征，还进一步了解了糖尿病患者神经运动控制缺陷。最终，在糖尿病人群中进行此类分析有助于指导预防糖尿病足的治疗干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Foot Health Professions-Podiatry

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： The Foot is an international peer-reviewed journal covering all aspects of scientific approaches and medical and surgical treatment of the foot. The Foot aims to provide a multidisciplinary platform for all specialties involved in treating disorders of the foot. At present it is the only journal which provides this inter-disciplinary opportunity. Primary research papers cover a wide range of disorders of the foot and their treatment, including diabetes, vascular disease, neurological, dermatological and infectious conditions, sports injuries, biomechanics, bioengineering, orthoses and prostheses.