{"title":"Novel Treatments for Patients With Relapsed/Refractory Multiple Myeloma.","authors":"Cesar Rodriguez, Donna Catamero","doi":"10.6004/jadpro.2023.14.3.14","DOIUrl":null,"url":null,"abstract":"<p><p>Therapeutic options for patients with multiple myeloma have multiplied in the past decade. However, multiple myeloma remains an incurable disease, and relapsed/refractory myeloma is characterized by genetic and cytogenetic alterations that drive resistance and result in progressively shorter durations of remission to each subsequent therapy. At JADPRO Live 2022, presenters discussed the multifactorial process for choosing the right therapy for a particular patient and strategies to manage unique treatment complications associated with novel treatment modalities used for patients with relapsed/refractory multiple myeloma.</p>","PeriodicalId":17176,"journal":{"name":"Journal of the Advanced Practitioner in Oncology","volume":"14 3","pages":"252-256"},"PeriodicalIF":0.0000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/ad/jadpro-14-252.PMC10184840.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Advanced Practitioner in Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6004/jadpro.2023.14.3.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Therapeutic options for patients with multiple myeloma have multiplied in the past decade. However, multiple myeloma remains an incurable disease, and relapsed/refractory myeloma is characterized by genetic and cytogenetic alterations that drive resistance and result in progressively shorter durations of remission to each subsequent therapy. At JADPRO Live 2022, presenters discussed the multifactorial process for choosing the right therapy for a particular patient and strategies to manage unique treatment complications associated with novel treatment modalities used for patients with relapsed/refractory multiple myeloma.
在过去的十年中,多发性骨髓瘤患者的治疗选择成倍增加。然而,多发性骨髓瘤仍然是一种无法治愈的疾病,复发/难治性骨髓瘤的特点是遗传和细胞遗传改变,这些改变会导致耐药性,并导致每次后续治疗的缓解持续时间逐渐缩短。在JADPRO Live 2022上,演讲者讨论了为特定患者选择正确治疗的多因素过程,以及与复发/难治性多发性骨髓瘤患者使用的新治疗方式相关的独特治疗并发症的管理策略。