Guillain-Barré Syndrome Following the BNT162b2 mRNA COVID-19 Vaccine.

Q3 Medicine Acta neurologica Taiwanica Pub Date : 2023-06-30
Hussein A Algahtani, Bader H Shirah, Yazeed K Albeladi, Reyadh K Albeladi
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Abstract

Purpose: The onset of the COVID-19 (SARS-CoV-2) pandemic in December 2019 created the need for multiple scientific research activities and clinical trials in an attempt to find solutions to mitigate the impact of the virus. One of the important tools to combat the virus is the development of vaccination programs. All types of vaccines have been associated with a mild to severe risk of neurological adverse events. One of these severe adverse events is Guillain-Barré syndrome.

Case report: Here, we describe a case of Guillain-Barré syndrome after the first dose of the BNT162b2 mRNA COVID-19 vaccine and review the literature to increase the current knowledge regarding this complication.

Conclusion: Guillain-Barré syndrome after COVID-19 vaccination is responsive to treatment. The benefits of administering the vaccine outweigh the risks. Due to the negative impact of COVID-19, it is essential to recognize the development of neurological complications that are potentially associated with vaccination, including Guillain-Barré syndrome.

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BNT162b2 mRNA COVID-19疫苗引起的格林-巴利综合征。
目的:2019年12月COVID-19 (SARS-CoV-2)大流行的爆发,需要开展多项科学研究活动和临床试验,试图找到减轻该病毒影响的解决方案。对抗这种病毒的重要手段之一是发展疫苗接种计划。所有类型的疫苗都与轻微到严重的神经不良事件风险相关。其中一种严重的不良事件是格林-巴罗综合征。病例报告:在这里,我们描述了一例在首次接种BNT162b2 mRNA COVID-19疫苗后出现格林-巴利综合征的病例,并回顾了文献,以增加目前对该并发症的了解。结论:COVID-19疫苗接种后吉兰-巴罗综合征对治疗有反应。接种疫苗的好处大于风险。由于COVID-19的负面影响,必须认识到可能与疫苗接种相关的神经系统并发症的发展,包括格林-巴-罗综合征。
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来源期刊
Acta neurologica Taiwanica
Acta neurologica Taiwanica Medicine-Neurology (clinical)
CiteScore
1.30
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0.00%
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