Nutrition Support in Critically Ill Cancer Patient Receiving Extracorporeal Membrane Oxygenation: A Case Report.

Ji-Yeon Kim, Gyung-Ah Wie, Kyoung-A Ryu, So-Young Kim
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Abstract

Adequate nutritional support is crucial in preventing complications and improving outcomes in critically ill patients. Extracorporeal membrane oxygenation (ECMO) is a mode of supportive care for patients with respiratory and/or cardiac failure. ECMO patients frequently exhibit a hypermetabolic state characterized by protein catabolism and insulin resistance, which can lead to malnutrition. Nutritional therapy is a vital component of intensive care, but its optimal administration for ECMO patients is unknown. This case report aims to provide insights into effective nutritional management for critically ill patients undergoing ECMO therapy. The patient was a 72-year-old male with a history of gastric and lung cancer who underwent a lobectomy complicated by bronchopleural fistula, postoperative bleeding, pneumonia, and acute respiratory distress syndrome (ARDS). The patient's nutritional status was assessed indicating a high risk of malnutrition, using the modified Nutrition Risk in the Critically Ill (mNUTRIC) Score. Nutritional support was administered based on the recommendations of European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN), with energy requirements set at 25-30 kcal/kg/d and protein requirements set at 1.2-2.0 g/kg/day. The patient received parenteral nutrition until the enteral nutrition target amount was reached, with zinc supplements for wound healing. The study highlights the need for further research on proactive and effective nutritional support for ECMO patients to improve compliance and prognosis.

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接受体外膜氧合的危重癌症患者的营养支持1例。
充足的营养支持对于预防重症患者并发症和改善预后至关重要。体外膜氧合(ECMO)是呼吸和/或心力衰竭患者的一种支持性护理模式。ECMO患者经常表现出以蛋白质分解代谢和胰岛素抵抗为特征的高代谢状态,这可能导致营养不良。营养治疗是重症监护的重要组成部分,但其对ECMO患者的最佳管理尚不清楚。本病例报告旨在为接受ECMO治疗的危重患者提供有效的营养管理见解。患者为72岁男性,既往有胃癌和肺癌病史,行肺叶切除术合并支气管胸膜瘘、术后出血、肺炎和急性呼吸窘迫综合征(ARDS)。使用改良的危重症营养风险评分(mNUTRIC)评估患者的营养状况,显示营养不良的高风险。根据欧洲临床营养与代谢学会(ESPEN)和美国肠外和肠内营养学会(ASPEN)的建议给予营养支持,能量需求设定为25-30 kcal/kg/d,蛋白质需求设定为1.2-2.0 g/kg/d。患者接受肠外营养,直至达到肠内营养目标量,并补充锌以促进伤口愈合。该研究强调需要进一步研究ECMO患者积极有效的营养支持,以提高依从性和预后。
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