A global federated real-world data and analytics platform for research.

IF 2.5 Q2 HEALTH CARE SCIENCES & SERVICES JAMIA Open Pub Date : 2023-07-01 DOI:10.1093/jamiaopen/ooad035
Matvey B Palchuk, Jack W London, David Perez-Rey, Zuzanna J Drebert, Jessamine P Winer-Jones, Courtney N Thompson, John Esposito, Brecht Claerhout
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引用次数: 4

Abstract

Objective: This article describes a scalable, performant, sustainable global network of electronic health record data for biomedical and clinical research.

Materials and methods: TriNetX has created a technology platform characterized by a conservative security and governance model that facilitates collaboration and cooperation between industry participants, such as pharmaceutical companies and contract research organizations, and academic and community-based healthcare organizations (HCOs). HCOs participate on the network in return for access to a suite of analytics capabilities, large networks of de-identified data, and more sponsored trial opportunities. Industry participants provide the financial resources to support, expand, and improve the technology platform in return for access to network data, which provides increased efficiencies in clinical trial design and deployment.

Results: TriNetX is a growing global network, expanding from 55 HCOs and 7 countries in 2017 to over 220 HCOs and 30 countries in 2022. Over 19 000 sponsored clinical trial opportunities have been initiated through the TriNetX network. There have been over 350 peer-reviewed scientific publications based on the network's data.

Conclusions: The continued growth of the TriNetX network and its yield of clinical trial collaborations and published studies indicates that this academic-industry structure is a safe, proven, sustainable path for building and maintaining research-centric data networks.

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一个全球联合的真实世界数据和分析研究平台。
目的:本文描述了用于生物医学和临床研究的可扩展、高性能、可持续的全球电子健康记录数据网络。材料和方法:TriNetX创建了一个以保守的安全和治理模型为特征的技术平台,促进了行业参与者之间的协作和合作,例如制药公司和合同研究组织,以及学术和社区医疗保健组织(hco)。hco加入网络,作为回报,他们可以使用一套分析功能、大型去识别数据网络和更多赞助的试用机会。行业参与者提供财务资源来支持、扩展和改进技术平台,以换取对网络数据的访问,从而提高临床试验设计和部署的效率。TriNetX是一个不断发展的全球网络,从2017年的55个hco和7个国家扩展到2022年的220多个hco和30个国家。通过TriNetX网络启动了超过19000个赞助的临床试验机会。基于该网络的数据,已有超过350篇同行评议的科学出版物。结论:TriNetX网络的持续增长及其临床试验合作和发表的研究成果的产量表明,这种学术-产业结构是建立和维护以研究为中心的数据网络的安全,成熟,可持续的途径。
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来源期刊
JAMIA Open
JAMIA Open Medicine-Health Informatics
CiteScore
4.10
自引率
4.80%
发文量
102
审稿时长
16 weeks
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