WITHDRAWN: The Anticancer Mechanism of Terpenoid-based Drug Candidates: Focus on Tumor Microenvironment

IF 2.6 4区 医学 Q3 CHEMISTRY, MEDICINAL Anti-cancer agents in medicinal chemistry Pub Date : 2025-01-01 DOI:10.2174/1871520623666230522163123
Yu Xin, Ran Huo, Wenlong Su, Wei Xu, Zhidong Qiu, Weinan Wang, Ye Qiu
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Abstract

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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萜类候选药物的抗癌机制:以肿瘤微环境为重点。
癌症被认为是全球范围内对人类生命最致命的威胁。尽管在手术、化疗、放疗和免疫治疗领域已经建立了多种治疗癌症的策略,但从天然产物中发现新的治疗药物由于其独特的功能机制和潜在的低副作用,仍然是抗癌治疗的基础。萜类化合物是最多样化和大量的天然产物之一,已被证明在癌症治疗中有前景。一些萜类化合物已经经过了多个阶段的临床试验,有些甚至被批准为抗癌药物,但这些研究大多强调对肿瘤细胞的直接作用,而对其对肿瘤微环境(TME)的全身作用关注较少。因此,我们在本文中招募了萜类化合物的专利药物和候选药物,并总结了它们的一般抗肿瘤机制,其中对TME的调节作用是重点。最后,对萜类化合物的药理作用及其在免疫治疗中的潜在益处进行了展望,为今后萜类天然产物的进一步研究提供参考。关键词。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Anti-cancer agents in medicinal chemistry
Anti-cancer agents in medicinal chemistry ONCOLOGY-CHEMISTRY, MEDICINAL
CiteScore
5.10
自引率
3.60%
发文量
323
审稿时长
4-8 weeks
期刊介绍: Formerly: Current Medicinal Chemistry - Anti-Cancer Agents. Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents. Each issue contains a series of timely in-depth reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication. Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.
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