Transmission of SARS-CoV-2 from mother to fetus or neonate: What to know and what to do?

IF 2.9 3区 医学 Q1 PEDIATRICS Seminars in Fetal & Neonatal Medicine Pub Date : 2023-02-01 DOI:10.1016/j.siny.2023.101429
Daniele De Luca , Christelle Vauloup-Fellous , Alexandra Benachi , Alexandre Vivanti
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引用次数: 5

Abstract

SARS-CoV-2 can be vertically transmitted from the mother to the fetus and the neonate. This transmission route is rare compared to the environmental or horizontal spread and therefore, the risk can be deemed inconsequential by some medical providers. However, severe, although just as rare, feto-neonatal consequences are possible: fetal demise, severe/critical neonatal COVID-19 and multi-inflammatory syndrome (MIS-N) have been described. Therefore, it is important for the clinicians to know the mechanism of vertical transmission, how to recognize this, and how to deal with neonatal COVID-19 and MIS-N. Our knowledge about this field has significantly increased in the last three years. This is a summary of the pathophysiology, diagnostics, and therapeutics of vertical SARS-CoV-2 transmission that clinicians apply in their clinical practice.

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SARS-CoV-2从母亲传播给胎儿或新生儿:应该知道什么和做什么?
严重急性呼吸系统综合征冠状病毒2型可以从母亲垂直传播给胎儿和新生儿。与环境或水平传播相比,这种传播途径是罕见的,因此,一些医疗提供者可能认为这种风险无关紧要。然而,胎儿-新生儿的严重后果(尽管同样罕见)是可能的:胎儿死亡、严重/危重新生儿新冠肺炎和多炎症综合征(MIS-N)已被描述。因此,临床医生了解垂直传播的机制、如何认识这一点以及如何应对新生儿新冠肺炎和MIS-N是很重要的。在过去的三年里,我们对这一领域的了解显著增加。这是临床医生在临床实践中应用的严重急性呼吸系统综合征冠状病毒2型垂直传播的病理生理学、诊断和治疗的总结。
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来源期刊
CiteScore
6.40
自引率
3.30%
发文量
49
审稿时长
6-12 weeks
期刊介绍: Seminars in Fetal & Neonatal Medicine (formerly Seminars in Neonatology) is a bi-monthly journal which publishes topic-based issues, including current ''Hot Topics'' on the latest advances in fetal and neonatal medicine. The Journal is of interest to obstetricians and maternal-fetal medicine specialists. The Journal commissions review-based content covering current clinical opinion on the care and treatment of the pregnant patient and the neonate and draws on the necessary specialist knowledge, including that of the pediatric pulmonologist, the pediatric infectious disease specialist, the surgeon, as well as the general pediatrician and obstetrician. Each topic-based issue is edited by an authority in their field and contains 8-10 articles. Seminars in Fetal & Neonatal Medicine provides: • Coverage of major developments in neonatal care; • Value to practising neonatologists, consultant and trainee pediatricians, obstetricians, midwives and fetal medicine specialists wishing to extend their knowledge in this field; • Up-to-date information in an attractive and relevant format.
期刊最新文献
Advocating for neonatology presence at births between 20 and 25 weeks of gestation. High-frequency jet ventilation in ELBW infants: A review and update. Assessment of Global Burden due to neonatal encephalopathy: An economic evaluation. Late preterm and early term birth: Challenges and dilemmas in clinical practice. Neonatal delirium.
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