Time to Death and Its Predictors Among Infants in Ethiopia: Multilevel Mixed-Effects Parametric Survival Analysis Using the 2019 Ethiopian Mini Demographic Health Survey.

IF 1.7 Q2 PEDIATRICS Pediatric health, medicine and therapeutics Pub Date : 2023-01-01 DOI:10.2147/PHMT.S402154
Befekadu Oyato, Husen Zakir, Dursa Hussein, Tasfaye Lemma, Mukemil Awol
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Abstract

Introduction: Three years ahead of the plan, Ethiopia has met Millennium Development Goal 4 of reducing under-five mortality. Additionally, the nation is on track to achieve the Sustainable Development Goal of putting an end to preventable child mortality. Despite this, recent data from the nation showed that there were 43 infant deaths for every 1000 live births. Moreover, the country has fallen short of the 2015 Health Sector Transformation Plan goal, with an anticipated infant mortality rate of 35 deaths per 1000 live births in 2020. Thus, this study aims to identify the time to death and its predictors among Ethiopian infants.

Methods: This study used the 2019 Mini-Ethiopian Demographic and Health Survey data set to conduct a retrospective study. The analysis used survival curves and descriptive statistics. Multilevel mixed-effects parametric survival analysis was applied to identify the predictors of infant mortality.

Results: The estimated mean survival time of infants was 11.3 months (95% CI: 11.1, 11.4). Women's current pregnancy status, family size, age of women, previous birth interval, place of delivery, and mode of delivery were significant individual-level predictors of infant mortality. Infants born with less than 24 months' birth interval had a 2.29 times higher estimated risk of death (AHR = 2.29, 95% CI: 1.05, 5.02). Infants born at home were 2.48 times more likely to die than those born in a health facility (AHR = 2.48, 95% CI: 1.03, 5.98). At the community level, women's education was the only statistically significant predictor of infant death.

Conclusion: The risk of infant death was higher before the first month of life, typically shortly after birth. Healthcare programs should put a strong emphasis on efforts to space out births and make institutional delivery services more readily accessible to mothers in Ethiopia to address the infant mortality challenges.

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埃塞俄比亚婴儿的死亡时间及其预测因素:使用2019年埃塞俄比亚迷你人口健康调查的多层次混合效应参数生存分析
导言:埃塞俄比亚比计划提前三年实现了千年发展目标4,即降低五岁以下儿童死亡率。此外,该国正在实现消除可预防的儿童死亡率的可持续发展目标。尽管如此,该国最近的数据显示,每1000名活产婴儿中有43名婴儿死亡。此外,该国未能实现2015年《卫生部门转型计划》的目标,预计到2020年婴儿死亡率为每1000例活产35例死亡。因此,本研究旨在确定埃塞俄比亚婴儿的死亡时间及其预测因素。方法:本研究使用2019年迷你埃塞俄比亚人口与健康调查数据集进行回顾性研究。分析采用生存曲线和描述性统计。应用多水平混合效应参数生存分析来确定婴儿死亡率的预测因子。结果:估计婴儿的平均生存时间为11.3个月(95% CI: 11.1, 11.4)。妇女目前的妊娠状况、家庭规模、妇女年龄、以前的生育间隔、分娩地点和分娩方式是婴儿死亡率的显著个人水平预测因子。出生间隔小于24个月的婴儿的估计死亡风险高2.29倍(AHR = 2.29, 95% CI: 1.05, 5.02)。在家中出生的婴儿死亡的可能性是在卫生机构出生的婴儿的2.48倍(AHR = 2.48, 95% CI: 1.03, 5.98)。在社区一级,妇女受教育程度是婴儿死亡的唯一具有统计学意义的预测指标。结论:婴儿死亡的风险在出生后第一个月前较高,通常在出生后不久。在埃塞俄比亚,医疗保健项目应大力强调间隔分娩的努力,并使产妇更容易获得机构分娩服务,以应对婴儿死亡率的挑战。
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