The Relationship Between Cardiovascular Disease Risk and Major Depression.

IF 1 4区医学 Q4 CLINICAL NEUROLOGY Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2023-01-01 DOI:10.29399/npa.28191

Bilge Targıtay Ozturk, Fatih Ozel, Tutku Yaras, Burcu Ekinci, Yavuz Oktay, Elif Onur Aysevener, Tunc Alkın, Neşe Direk

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Abstract

Introduction: Cardiovascular risk in depression has been investigated in small clinical samples and population-based studies revealing inconclusive results. However, cardiovascular risk in drug-naive depressed patients has not been tested extensively.

Methods: Body mass index-based Framingham Cardiovascular Risk Scores and soluble intercellular adhesion molecule-1 (sICAM-1) levels were used to assess the risk of cardiovascular disease in drug-naive depressed patients and healthy volunteers.

Conclusion: There were no significant differences in Framingham Cardiovascular Risk Scores and individually assessed risk variables between patients and healthy controls (HC). Both groups were comparable in terms of sICAM-1.

Results: The widely recognized association between cardiovascular risk and major depression might be more prominent in older depressed patients and patients with recurring episodes.

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心血管疾病风险与重度抑郁症的关系

前言:抑郁症的心血管风险已经在小临床样本和基于人群的研究中进行了调查，结果显示不确定。然而，未用药抑郁症患者的心血管风险尚未得到广泛的测试。方法:采用基于身体质量指数的Framingham心血管风险评分和可溶性细胞间粘附分子-1 (sICAM-1)水平评估未用药抑郁症患者和健康志愿者的心血管疾病风险。结论:患者与健康对照组(HC)在Framingham心血管风险评分和单独评估的风险变量方面无显著差异。两组在sICAM-1方面具有可比性。结果:心血管风险与重度抑郁症之间的关联在老年抑郁症患者和反复发作的患者中可能更为突出。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Noropsikiyatri Arsivi-Archives of Neuropsychiatry CLINICAL NEUROLOGY-

CiteScore

1.70

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Neuropsychiatry (Arch Neuropsychiatry) is the official journal of the Turkish Neuropsychiatric Society. It is published quarterly, and four editions annually constitute a volume. Archives of Neuropsychiatry is a peer reviewed scientific journal that publishes articles on psychiatry, neurology, and behavioural sciences. Both clinical and basic science contributions are welcomed. Submissions that address topics in the interface of neurology and psychiatry are encouraged. The content covers original research articles, reviews, letters to the editor, and case reports.