Unresolved issues in the management of human papillomavirus-associated mucosal high-grade pre-cancers

IF 4.7 Q1 VIROLOGY Tumour Virus Research Pub Date : 2023-06-01 DOI:10.1016/j.tvr.2022.200250
Charles JN. Lacey
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引用次数: 0

Abstract

This article reviews human papillomavirus-associated mucosal high-grade pre-cancers and their management. It examines pre-cancer classification systems, the natural history of HPV-associated pre-cancers, the various types of management and treatment for HPV pre-cancers, the various mucosal site-specific considerations, and then some of the unresolved issues. Different conclusions are reached for each of the relevant mucosal sites, which are cervix, vagina, vulva, anus, penis and oro-pharynx, and indeed there are differing volumes of evidence relating to each of these sites, and thus differing degrees of certainty/uncertainty in the recommendations.

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人乳头瘤病毒相关的粘膜高级别癌前病变治疗中尚未解决的问题
本文综述了人乳头瘤病毒相关的粘膜高级癌前病变及其治疗。它检查了癌前分类系统、与HPV相关的癌前自然史、HPV癌前的各种管理和治疗类型、各种粘膜特定部位的考虑因素,以及一些尚未解决的问题。对于每个相关的粘膜部位,即宫颈、阴道、外阴、肛门、阴茎和口咽,都得出了不同的结论,事实上,这些部位的证据量不同,因此建议的确定性/不确定性程度也不同。
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来源期刊
Tumour Virus Research
Tumour Virus Research Medicine-Infectious Diseases
CiteScore
6.50
自引率
2.30%
发文量
16
审稿时长
56 days
期刊最新文献
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