Whorling-sclerosing meningioma invading skull bone and subcutaneous tissue with an incidental toxoplasmosis: A case report.

Abstract

Whorling-sclerosing meningioma (WSM) is a rare type of meningothelial tumor. Worldwide, only 31 cases have been reported. The diagnosis of this rare meningioma subtype is based principally on microscopic findings, wherein up to 70% of the tumor tissue should be formed by thick whorls of collagen. Notably, there is still disagreement about whether to consider this entity a benign meningioma (grade 1) or a meningioma with higher malignant potential (grade 2 or even grade 3). In fact, the paucity of reported WSM cases and, consequently, the lack of information about their follow up make their diagnosis and treatment challenging. Herein, we document the first case of WSM in Syria in a 75-year-old woman with an incidental finding of Toxoplasma gondii. Although WSM has not been mentioned in the recent World Health Organization classification of central nervous system tumors, it should be recognized to avoid incorrect diagnosis and spare the patients unnecessary radiotherapy and chemotherapy.