Cardiac rehabilitation in coronary artery bypass grafting patients: Effect of eight weeks of moderate-intensity continuous training versus high-intensity interval training.

IF 2.1 4区医学 Q3 HEMATOLOGY Clinical hemorheology and microcirculation Pub Date : 2023-01-01 DOI:10.3233/CH-221605

Neda Shafie, Negin Kordi, Keivan Gadruni, Ziba SalehFard, Friedrich Jung, Naser Heidari

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引用次数: 1

Abstract

Background: Physical training in patients with heart failure can affect hemodynamic, cardiac and angiogenesis parameters.

Objective: The aim of the present study was to investigate the effects of traditional moderate-intensity rehabilitation training and interval training on some angiogenesis factors in coronary artery bypass graft (CABG) patients.

Methods: Thirty CABG patients (mean age±SD, 55±3 years) were randomly assigned to one of three groups: high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT) or the control group. After the initial assessments, eligible patients in the experimental groups (HIIT and MICT) performed exercise training for 8 weeks, while the control group did not. Angiogenesis and angiostatic indices, including pro-adrenomedullin (pro-ADM), basic fibroblast growth factor (bFGF), and endostatin, were then measured.

Results: The results showed no significant difference between pro-ADM in the HIIT and MICT groups (P = 0.99), but a significant difference was found between MICT and the control group and between HIIT and the control group (P = 0.001). There is also no significant difference between the bFGF levels in the HIIT and MICT training groups (P = 1.00), but the changes in this factor between the training groups and the control group were significant (P = 0.001). There was a significant difference between the levels of endostatin in all three groups.

Conclusions: Two methods of cardiac rehabilitation (HIIT and MICT) may be useful for the recovery of patients with coronary artery bypass grafting. This improvement manifested itself in changes in angiogenesis and angiostatic indices in this study. However, more extensive studies are needed to investigate the effects of these two types of rehabilitation programs on other indicators of angiogenesis and angiostatic.

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冠状动脉旁路移植术患者的心脏康复:8周中等强度连续训练与高强度间歇训练的效果

背景:心力衰竭患者的体育锻炼可以影响血液动力学、心脏和血管生成参数。目的:探讨传统中等强度康复训练和间歇训练对冠状动脉旁路移植术(CABG)患者血管生成因子的影响。方法:30例CABG患者(平均年龄±SD, 55±3岁)随机分为三组:高强度间歇训练(HIIT)组或中强度连续训练(MICT)组或对照组。经过初步评估，实验组(HIIT和MICT)中符合条件的患者进行了8周的运动训练，而对照组则没有。测量血管生成和血管抑制指标，包括促肾上腺髓质素(pro-ADM)、碱性成纤维细胞生长因子(bFGF)和内皮抑素。结果:HIIT组与MICT组pro-ADM差异无统计学意义(P = 0.99)，而MICT组与对照组、HIIT组与对照组间pro-ADM差异有统计学意义(P = 0.001)。HIIT训练组和MICT训练组的bFGF水平也无显著差异(P = 1.00)，但训练组和对照组之间bFGF水平的变化有显著性(P = 0.001)。三组的内皮抑素水平有显著差异。结论:HIIT和MICT两种心脏康复方法可能有助于冠状动脉搭桥术患者的康复。在本研究中，这种改善表现在血管生成和血管静止指数的变化上。然而，需要更广泛的研究来调查这两种类型的康复计划对血管生成和血管抑制的其他指标的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical hemorheology and microcirculation 医学-外周血管病

CiteScore

4.30

自引率

33.30%

发文量

170

期刊介绍： Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research. The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process. Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.