[Neurological aspects of diagnosis and treatment of motor alalia].

A A Skoromets, A P Skoromets, O V Yurlova, G P Pravdukhina, S A Golochalova
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Abstract

Objective: To analyze the causes of violations of expressive speech in children 4-5 years old, to assess changes in neurological status in children with motor alalia without and during treatment with Cellex.

Material and methods: Two groups of patients were recruited: the main group (n=30; treatment; Cellex) and the control group (n=12; without Cellex). The drug was administered in the first half of the day by 1.0 ml subcutaneously, 10 days, daily. The patient's visit card was analyzed 4 times: before treatment, 10 days later, 1 and 2 months after the start of treatment. Statistical hypotheses were tested using the χ2 and Fisher criterions, the odds ratio (OR) and the 95% confidence interval (CI) OR were determined.

Results: In more than half of the cases, violations of the neurological status, the burden of the perinatal period, a decrease in cognitive tests, and a lack of fine motor skills were revealed. Left-handedness or two-handedness, overload of viewing or listening to gadgets from the age of up to a year, violations of opercular praxis were almost always noted. The effect of the drug Cellex on the «launch of speech» in children with motor alalia has been shown. It has been established that the drug is well tolerated, has no adverse side effects and has a positive effect on the «launch of speech». The progress of the dynamics of speech development, progress in play and cognitive activity was observed in all children of the main group.

Conclusion: The use of the drug Cellex can be effective in the treatment of children with motor alalia.

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[运动异常的诊断和治疗的神经学方面]。
目的:分析4 ~ 5岁儿童表达性言语障碍的原因,评价运动障碍患儿在使用Cellex治疗前后神经系统状态的变化。材料与方法:选取两组患者:主组(n=30);治疗;Cellex)和对照组(n=12;没有Cellex)。该药于当天前半部分皮下给药1.0 ml,连续10天,每日给药。分析患者就诊卡4次:治疗前、治疗后10天、治疗开始后1个月和2个月。采用χ2和Fisher标准检验统计假设,确定优势比(OR)和95%置信区间(CI) OR。结果:在半数以上的病例中,发现了神经系统状况的破坏,围产期的负担,认知测试的减少,以及缺乏精细运动技能。左撇子或双手撇子,从一岁开始过度看或听电子产品,几乎总是会注意到违反了眼部活动。药物Cellex对运动障碍儿童的“语言启动”的影响已经被证明。目前已经证实,这种药物耐受性良好,没有不良副作用,对“启动语言”有积极作用。在主组的所有儿童中都观察到语言发展的动态进展,游戏和认知活动的进展。结论:应用赛乐司治疗小儿运动障碍有较好的疗效。
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来源期刊
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Medicine-Psychiatry and Mental Health
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