Effect of SARS-CoV-2 infection on the liver.

Adekunle Sanyaolu, Aleksandra Marinkovic, Abu Fahad Abbasi, Stephanie Prakash, Risha Patidar, Priyank Desai, Martina Williams, Abdul Jan, Kareem Hamdy, Rachael Solomon, Vyshnavy Balendra, Maaz Ansari, Omar Shazley, Nasar Khan, Rochelle Annan, Yashika Dixon, Chuku Okorie, Afolabi Antonio
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引用次数: 1

Abstract

There have been numerous concerns about the disease and how it affects the human body since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began in December 2019. The impact of SARS-CoV-2 on the liver is being carefully investigated due to an increase in individuals with hepatitis and other liver illnesses, such as alcoholic liver disease. Additionally, the liver is involved in the metabolism of numerous drugs used to treat comorbidities and coronavirus disease 2019 (COVID-19). Determining how SARS-CoV-2 affects the liver and what factors place individuals with COVID-19 at a higher risk of developing liver problems are the two main objectives of this study. This evaluation of the literature included research from three major scientific databases. To provide an update on the current impact of COVID-19 on the liver, data was collected and relevant information was incorporated into the review. With more knowledge about the effect of the disease on the liver, better management and therapeutics can be developed, and education can ultimately save lives and reduce the long-term impact of the pandemic on our population.

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SARS-CoV-2感染对肝脏的影响
自2019年12月严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)大流行开始以来,人们对这种疾病及其对人体的影响有很多担忧。由于肝炎和其他肝脏疾病(如酒精性肝病)患者的增加,正在仔细调查SARS-CoV-2对肝脏的影响。此外,肝脏还参与许多用于治疗合并症和2019年冠状病毒病(COVID-19)的药物的代谢。确定SARS-CoV-2如何影响肝脏以及哪些因素使COVID-19患者患肝脏问题的风险更高是本研究的两个主要目标。对文献的评估包括来自三个主要科学数据库的研究。为了提供关于当前COVID-19对肝脏影响的最新信息,收集了数据并将相关信息纳入了综述。随着对该疾病对肝脏影响的更多了解,可以开发更好的管理和治疗方法,教育最终可以挽救生命并减少该流行病对我们人口的长期影响。
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