[Cerebral-meningeal hemorrhage secondary to snakebite envenomation: about two cases at the Sourô Sanou Teaching Hospital in Bobo-Dioulasso, Burkina Faso].

Pingdéwendé Victor Ouedraogo, Catherine Traore, Abdoul Aziz Savadogo, Wend Pagnangdé Abraham Hermann Bagbila, Adama Galboni, Abaz Ouedraogo, Ibrahima Stéphane Sere, Athanase Millogo
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Abstract

Background: Envenomation by snakebite is a public health problem in developing countries. Neurovascular complications are uncommon. We report two cases of hemorrhagic stroke at the Sourô Sanou Teaching Hospital in Bobo-Dioulasso, which complicate an envenomation.

Clinical description: The first patient was a 60-year-old woman with no history, who had been admitted 2 hours after snakebite for gingivorrhagia and consciousness disorders. Clinical examination found coma (GCS 7/15) and tetraparesis. The second patient was a 50-year-old woman with no history, who had been admitted one week after snakebite with digestive bleeding. Clinical examination found right hemiplegia and meningeal syndrome. Both patients presented hemorrhagic stroke on brain CT-scan but hemostasis assessment was normal. They received polyvalent antivenom and symptomatic treatment. The outcome was favorable for survival but with sequelae like tetraparesis for first patient and hemiparesis for second patient.

Discussion - conclusion: The hemorrhagic strokes are rare complications of snake envenomation. Venomous toxins can directly lead to the rupture of intracranial vessels apart of abnormalities of hemostasis. However, the morbidity and mortality related to envenomation by snake bite remains high in our environment.

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[蛇咬伤致脑膜出血:布基纳法索Bobo-Dioulasso Sourô Sanou教学医院的两例]。
背景:蛇咬伤中毒是发展中国家的一个公共卫生问题。神经血管并发症并不常见。我们报告两例出血性中风在Sourô萨努教学医院在Bobo-Dioulasso,这复杂化了中毒。临床描述:第一位患者为60岁女性,无病史,因牙龈出血和意识障碍在蛇咬伤后2小时入院。临床检查发现昏迷(GCS 7/15)和四肢麻痹。第二名患者是一名50岁的女性,没有病史,在蛇咬伤后一周因消化道出血入院。临床检查发现右侧偏瘫及脑膜综合征。两例患者均表现为出血性脑卒中,但止血评估正常。给予多价抗蛇毒血清和对症治疗。结果有利于生存,但有后遗症,如四瘫的第一个病人和偏瘫的第二个病人。讨论-结论:出血性中风是蛇中毒的罕见并发症。除止血异常外,有毒毒素可直接导致颅内血管破裂。然而,在我们的环境中,与蛇咬伤有关的发病率和死亡率仍然很高。
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