Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial.

IF 1.9 Q3 CHEMISTRY, MEDICINAL Avicenna Journal of Phytomedicine Pub Date : 2023-03-01 DOI:10.22038/AJP.2022.21316
Parkha Riaz Nasrullah, Bismillah Sehar, Mahpara Safdar, Sadia Fatima, Falak Zeb, Jahan Shah, Atif Ali Khan Khalil, Bilal Ahmed, Ali Saad R Alsubaie, Muhammad Haidar Zaman
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Abstract

Objective: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia.

Materials and methods: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides >150 mg/dl and BMI >25, of either sex, aged 30-50 years, who were recruited through written consent. The patients were divided into two groups (n=20 each): the ADP and the control group (CG). All patients received the doctor's prescribed class A statin (Rosuvastatin/ Atorvastatin) 10 mg/day, while 2.7 g ADP was given on daily basis before breakfast with lukewarm water for 40 days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after 20 and 40 days. Data were analyzed by using SPSS and GraphPad Prism.

Results: ADP significantly reduced body weight (p<0.001), BMI (p<0.001), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=0.000) decreased the serum level of total cholesterol and low-density lipoprotein.

Conclusion: ADP may have the potential to improve dyslipidemia and obesity.

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Ajwa枣核粉对高脂血症患者身体成分、血脂和血压的影响:一项随机临床试验。
目的:评价阿杰瓦红枣核散对高脂血症患者血脂、身体成分及血压的影响。材料和方法:这项随机对照临床研究对40名总胆固醇>200 mg/dl、甘油三酯>150 mg/dl、BMI>25的患者进行,这些患者年龄在30-50岁之间,属于任何性别,通过书面同意招募。将患者分为两组(每组n=20):ADP组和对照组(CG)。所有患者均接受医生处方的A类他汀类药物(瑞舒伐他汀/阿托伐他汀)10mg/天,而每天早餐前用温水给予2.7g ADP,持续40天,对照组接受等量的小麦粉。在基线、20天和40天后测定身体成分、血压和脂质状况。结果:ADP能显著减轻体重(P结论:ADP可能具有改善血脂异常和肥胖的潜力。
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来源期刊
Avicenna Journal of Phytomedicine
Avicenna Journal of Phytomedicine CHEMISTRY, MEDICINAL-
CiteScore
3.40
自引率
4.50%
发文量
17
审稿时长
6 weeks
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