Managing the older adult with inflammatory bowel disease: is age just a number?

IF 2.6 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Current Opinion in Gastroenterology Pub Date : 2023-07-01 Epub Date: 2023-05-23 DOI:10.1097/MOG.0000000000000943
Helen Bermudez, Adam S Faye, Bharati Kochar
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Abstract

Purpose of review: This review summarizes the most recent literature on older adults with inflammatory bowel diseases (IBD). Additionally, we review geriatric syndromes that may be pertinent to the management of older adults with IBD.

Recent findings: Traditionally chronological age has been used to risk stratify older adults with IBD, however physiologic status, including comorbidities, frailty, and sarcopenia, are more closely associated with clinical outcomes for older adults. Delaying care for and undertreating older adults with IBD based upon advanced chronologic age alone is associated with worse outcomes, including increased mortality. Treatment decisions should be made considering physiologic status, with an understanding of the differential risks associated with both ongoing disease and treatment. As such, there is an increasing recognition of the impact geriatric syndromes have on older adults with IBD, which need to be further explored.

Summary: Older adults with IBD are less likely to receive advanced therapies and timely surgery. They are also more likely to have adverse outcomes despite having similar disease courses to younger adults with IBD. Focusing on biological age as opposed to chronological age can shift this trajectory and improve quality of care for this growing population of patients with IBD.

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管理患有炎症性肠病的老年人:年龄只是一个数字吗?
综述目的:本综述总结了关于老年人炎症性肠病(IBD)的最新文献。此外,我们还回顾了可能与患有IBD的老年人的管理有关的老年综合征。最近的研究结果:传统上,年龄被用于对患有IBD老年人进行风险分层,但生理状态,包括合并症、虚弱和少肌症,与老年人的临床结果更密切相关。仅根据晚期年龄延迟治疗和治疗患有IBD的老年人与更糟糕的结果有关,包括死亡率增加。治疗决策应考虑生理状态,并了解与正在进行的疾病和治疗相关的不同风险。因此,人们越来越认识到老年综合征对患有IBD的老年人的影响,这一点需要进一步探索。摘要:患有IBD的老年人不太可能接受先进的治疗和及时的手术。尽管他们的病程与患有IBD的年轻人相似,但他们也更有可能出现不良后果。关注生物学年龄而不是按时间顺序排列的年龄可以改变这一轨迹,并提高IBD患者群体的护理质量。
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来源期刊
Current Opinion in Gastroenterology
Current Opinion in Gastroenterology 医学-胃肠肝病学
CiteScore
5.30
自引率
0.00%
发文量
137
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in Gastroenterology features hand-picked review articles from our team of expert editors. With twelve disciplines published across the year – including gastrointestinal infections, nutrition and inflammatory bowel disease – every issue also contains annotated references detailing the merits of the most important papers.
期刊最新文献
Updates on therapeutic endoscopic ultrasound. Tight junction regulation, intestinal permeability, and mucosal immunity in gastrointestinal health and disease. Endoscopic therapies for bariatric surgery complications. Gastroduodenal injury and repair mechanisms. Nutritional aspects in patients with gastroparesis.
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