Acute Kidney Injury and Mid-term Outcomes After Extra-Cardiac Fontan Conversion.

IF 1.5 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pediatric Cardiology Pub Date : 2024-10-01 Epub Date: 2023-06-24 DOI:10.1007/s00246-023-03220-y

Tatsuya Kunigo, Risa Oikawa, Minoru Nomura

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Abstract

The aim of this study was to investigate the association of postoperative acute kidney injury and unplanned re-admission rate due to heart failure at 2 years follow-up in patients who had extra-cardiac Fontan conversion. This was a retrospective single-center study of patients who underwent conversion from classic Fontan to extra-cardiac Fontan between January 2014 and December 2021. Acute kidney injury was defined using the Kidney Disease Improving Global Outcomes criteria. A total of 47 patients underwent Fontan conversion. Acute kidney injury occurred in 22 patients (46.8%) and 5 patients with acute kidney injury needed renal replacement therapy. Unplanned re-admission rate at 2-year follow-up was significantly higher in patients with acute kidney injury even when renal function returned to baseline (8 [36.4%] vs. 3 [12.0%], p = 0.026 by the log-rank test). In conclusion, postoperative acute kidney injury after extra-cardiac Fontan conversion was associated with unplanned re-admission due to heart failure at 2-year follow-up even though renal function was recovered.

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心外丰坦转换术后的急性肾损伤和中期预后。

本研究旨在调查心外丰坦转换患者术后急性肾损伤与随访2年时因心力衰竭意外再入院率的关联。这是一项回顾性单中心研究，研究对象是2014年1月至2021年12月期间从经典Fontan转为心外Fontan的患者。急性肾损伤的定义采用肾脏疾病改善全球结果标准。共有47名患者接受了Fontan转换。22名患者（46.8%）出现急性肾损伤，5名急性肾损伤患者需要进行肾脏替代治疗。即使肾功能恢复到基线，急性肾损伤患者在2年随访期间的非计划再入院率也明显更高（8 [36.4%] vs. 3 [12.0%]，对数秩检验 p = 0.026）。总之，心外丰坦转换术后急性肾损伤与2年随访时因心力衰竭意外再次入院有关，即使肾功能已经恢复。

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来源期刊

Pediatric Cardiology 医学-小儿科

CiteScore

3.30

自引率

6.20%

发文量

258

审稿时长

12 months

期刊介绍： The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.