Clinical Characteristics of persistent geotropic horizontal direction-changing positional nystagmus: Experience in 189 participants.

IF 2.9 3区医学 Q2 NEUROSCIENCES Journal of Vestibular Research-Equilibrium & Orientation Pub Date : 2023-01-01 DOI:10.3233/VES-220086

Hao Peng, Liyi Wang, Haitao Song, Bo Gao, Yi Yang, Fan Lyu

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引用次数: 2

Abstract

Background: The etiology and mechanism of persistent geotropic horizontal direction-changing positional nystagmus (DCPN) are still unclear. Whether this pattern of nystagmus is a subtype of benign paroxysmal positional vertigo (BPPV) remains controversial.

Objective: The goal of this study was to observe the clinical characteristics of persistent geotropic horizontal DCPN involving the lateral semicircular canal.

Methods: The analysis was performed to participants with episodic positional vertigo in our clinic from 2014 to 2021. Participants were included via positional test. We observed and summarized the distribution data, vertigo history, follow-up tests, and recurrence situations of 189 persistent geotropic horizontal DCPN participants.

Results: The mean age at the first time showing of persistent geotropic horizontal DCPN was 56±14.7 and more women than men were affected by persistent geotropic horizontal DCPN (female-to-male ratio 2.4 : 1). Overall, 58.7% (57/94) of participants who came for the first-week follow-up test were asymptomatic. Thirty-three participants experienced recurrence (female-to-male ratio: 4.5 : 1). Fifty-three (28.0%) participants experienced the conversion of the patterns of DCPN in the history, the follow-up tests and the recurrence compared to the first showing of persistent geotropic horizontal DCPN. 24(12.1%) participants still experienced persistent geotropic horizontal DCPN attack in the follow-up tests and the recurrences without benign paroxysmal positional vertigo history.

Conclusion: Persistent geotropic horizontal DCPN affected more women than men. The persistent geotropic horizontal DCPN that with conversion to transient geotropic horizontal DCPN or to persistent apogeotropic horizontal DCPN might be a subtype of BPPV or in a stage of BPPV process. However, the persistent geotropic horizontal DCPN without conversion might be an independent disease that is not related to BPPV.

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189例持续性地向水平方向改变的体位性眼球震颤的临床特征。

背景:持续性地向水平方向改变位置性眼球震颤(DCPN)的病因和机制尚不清楚。这种类型的眼球震颤是否为良性阵发性位置性眩晕(BPPV)的亚型仍有争议。目的:观察累及外侧半规管的顽固性地向水平型DCPN的临床特点。方法:对2014年至2021年在我院就诊的阵发性位置性眩晕患者进行分析。参与者通过位置测试。我们观察并总结了189例持续性地向性水平DCPN患者的分布资料、眩晕史、随访检查和复发情况。结果:首次出现持续性地向性水平DCPN的平均年龄为56±14.7岁，女性多于男性(男女比例为2.4:1)。总体而言，58.7%(57/94)参加第一周随访测试的参与者无症状。33名参与者出现复发(男女比例:4.5:1)。53名(28.0%)参与者经历了历史上DCPN模式的转换，随访测试和复发，与首次显示持续性地向性水平DCPN相比。24例(12.1%)患者随访时有持续地向性水平DCPN发作，复发时无良性阵发性位置性眩晕史。结论:持续性地向性水平型DCPN女性多于男性。向瞬时地向水平DCPN或向持续地向水平DCPN转变的持续地向水平DCPN可能是BPPV的一个亚型或处于BPPV过程的一个阶段。然而，没有转化的持续地向性水平DCPN可能是一种与BPPV无关的独立疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Vestibular Research-Equilibrium & Orientation 医学-耳鼻喉科学

CiteScore

5.00

自引率

4.30%

发文量

审稿时长

>12 weeks

期刊介绍： Journal of Vestibular Research is a peer-reviewed journal that publishes experimental and observational studies, review papers, and theoretical papers based on current knowledge of the vestibular system. Subjects of the studies can include experimental animals, normal humans, and humans with vestibular or other related disorders. Study topics can include the following: Anatomy of the vestibular system, including vestibulo-ocular, vestibulo-spinal, and vestibulo-autonomic pathways Balance disorders Neurochemistry and neuropharmacology of balance, both at the systems and single neuron level Neurophysiology of balance, including the vestibular, ocular motor, autonomic, and postural control systems Psychophysics of spatial orientation Space and motion sickness Vestibular rehabilitation Vestibular-related human performance in various environments

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