[Somatic pathology in elderly and senile persons suffering from Alzheimer's disease and Alzheimer's type dementia.]

V S Myakotnykh, A P Sidenkova, E S Kravchenko, T A Borovkova, O M Khromtsova, V N Meshchaninov
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Abstract

In order to study the prevalence of chronic somatic age-associated pathology in elderly and senile people suffering from Alzheimer's type dementia with the presentation of the hypothesis of somatopsychic pathogenetic comorbidity observation and treatment, 217 patients were observed, conditionally divided into 2 comparable groups: with a definitive diagnosis of Alzheimer's disease (n=73) and with so-called Alzheimer's type dementia (n=144). Distinct differences in the variants of comorbid to the selected types of dementia of somatic pathology were determined, which had a negative impact not only in terms of the occurrence of cognitive disorders, but also in the future, during the formation of the most severe variants of dementia. In cases of Alzheimer's disease, pathological processes in the large intestine turned out to be leading, with Alzheimer's type dementia - diseases of the circulatory system and type 2 diabetes mellitus. Nevertheless, the diagnostic algorithm of patients with dementia should include the most comprehensive somatic examination, and treatment should affect not only the mental, but also the somatic sphere, taking into account the principles of a comprehensive geriatric assessment. With such approaches and under the condition of social well-being in the family, it is possible to achieve not only stabilization, but also some improvement in terms of psychopathological disorders, in particular with Alzheimer's type dementia.

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[老年痴呆症和阿尔茨海默氏型痴呆患者的躯体病理]
为了研究老年和老年阿尔茨海默氏型痴呆患者慢性躯体年龄相关病理的患病率,在躯体心理疾病共病观察和治疗的假设下,对217例患者进行了观察,有条件地分为2组:明确诊断为阿尔茨海默氏病(n=73)和所谓阿尔茨海默氏型痴呆(n=144)。确定了所选的躯体病理痴呆类型的合并症变体的明显差异,这不仅在认知障碍的发生方面具有负面影响,而且在未来最严重的痴呆变体形成过程中也具有负面影响。在阿尔茨海默病的病例中,大肠的病理过程被证明是主导的,导致阿尔茨海默病型痴呆——循环系统疾病和2型糖尿病。然而,痴呆症患者的诊断算法应包括最全面的躯体检查,治疗应不仅影响精神领域,还应影响躯体领域,同时考虑到综合老年评估的原则。通过这种方法,在家庭社会福利的条件下,不仅可以实现稳定,而且可以在精神病理障碍方面,特别是阿尔茨海默氏型痴呆症方面取得一定程度的改善。
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0.50
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发文量
131
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