[Knowledge about warfarin treatment in patients with atrial fibrillation or mechanical prosthetic valves].

Lady Rojana Vásquez Ortiz, Deysi Díaz Seijas, Natalia Emilia Gordillo Campos, Ana Elizabeth Aguilar Alban
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Abstract

Objective: To determine the degree of knowledge about warfarin treatment in patients with atrial fibrillation or with mechanical prosthetic valves.

Materials and methods: Descriptive, observational, cross-sectional study. The OAK test was applied to all adult patients with a diagnosis of atrial fibrillation or with mechanical prosthetic valves treated with warfarin, who attended the hematology consultation from May 17 to November 10, 2022, at the "Instituto Nacional Cardiovascular Carlos Alberto Peschiera Carrillo".

Results: A total of 150 patients participated, 64% were male, with a mean age of 60.3 ± 15 years, 45.3% with a diagnosis of atrial fibrillation and 54.7% with mechanical prosthetic valves. The mean OAK test score was 44.4% (8.4/19), only 6% (n=9) achieved a satisfactory score ≥75.0%, the percentage of correct answers according to dimensions was: 68 % in forms of use, 39.3% in interactions and complications and 41.1% in INR control. A 40.7% did not understand the meaning of the term INR and 81.3% did not know their optimal values.

Conclusions: The patient's degree of knowledge about warfarin treatment was inadequate; both in its use, interactions and complications. Considering that it is a difficult drug to use, due to its narrow therapeutic window and its multiple interactions, inadequate knowledge of its use may contribute to inappropriate anticoagulation.

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[心房颤动或机械瓣膜患者华法林治疗知识]。
目的:了解心房颤动患者或机械瓣膜置换术患者对华法林治疗的认知程度。材料和方法:描述性、观察性、横断面研究。OAK试验应用于2022年5月17日至11月10日在“Instituto Nacional Cardiovascular Carlos Alberto Peschiera Carrillo”参加血液学会诊的所有房颤诊断或使用华法林治疗机械假瓣膜的成年患者。结果:共150例患者参与研究,其中男性占64%,平均年龄60.3±15岁,45.3%诊断为房颤,54.7%诊断为机械假瓣膜。平均OAK测试得分为44.4%(8.4/19),只有6% (n=9)达到满意得分≥75.0%,各维度的正确答案比例为:使用形式68%,相互作用和并发症39.3%,INR对照41.1%。40.7%的人不理解术语INR的含义,81.3%的人不知道他们的最佳值。结论:患者对华法林治疗的认知程度不足;无论是在它的使用,相互作用和并发症。考虑到它是一种难以使用的药物,由于其狭窄的治疗窗口和多种相互作用,对其使用的认识不足可能导致不适当的抗凝。
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