{"title":"Enhancement of Visuospatial Working Memory by Transcranial Direct Current Stimulation on Prefrontal and Parietal Cortices.","authors":"Yousef Moghadas Tabrizi, Meysam Yavari Kateb, Shahnaz Shahrbanian","doi":"10.32598/bcn.2021.3275.1","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Previous studies have reported dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex (PPC) activation during the performance of spatial working memory (SWM), therefore this study aims to compare the effect of transcranial direct current stimulation (tDCS) between these two areas.</p><p><strong>Methods: </strong>Fifty-four healthy right-handed students (27 women, 27 men; age=24.3±0.2 years) were randomly assigned to an anodal group (n=27) and a sham group (n=27), each of these groups was divided into F4 (representing right DLPFC) or P4 (representing right PPC) subgroups, respectively. A computerized Corsi block tapping (CBT) task was used to measure SWM. The tDCS intervention consisted of five daily sessions with a direct current of 1.5 mA for 15 minutes on the F4 or P4 area of the brain at 24-hour intervals.</p><p><strong>Results: </strong>Significant enhancement of the SWM span as well as a faster response was observed after anodal tDCS in both the anterior and posterior direction. Moreover, stimulation of the left DLPFC induced a faster reaction time compared to the right PPC.</p><p><strong>Conclusion: </strong>Stimulation DLPFC and PPC, as an element of the frontoparietal network, showed SWM enhancement, with the DLPFC being more affected. Our finding provides new evidence to compare the effect of stimulation on the two main activated cortical areas during visual SWM.</p>","PeriodicalId":8701,"journal":{"name":"Basic and Clinical Neuroscience","volume":"14 1","pages":"129-136"},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/c3/BCN-14-129.PMC10279990.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Basic and Clinical Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32598/bcn.2021.3275.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Previous studies have reported dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex (PPC) activation during the performance of spatial working memory (SWM), therefore this study aims to compare the effect of transcranial direct current stimulation (tDCS) between these two areas.
Methods: Fifty-four healthy right-handed students (27 women, 27 men; age=24.3±0.2 years) were randomly assigned to an anodal group (n=27) and a sham group (n=27), each of these groups was divided into F4 (representing right DLPFC) or P4 (representing right PPC) subgroups, respectively. A computerized Corsi block tapping (CBT) task was used to measure SWM. The tDCS intervention consisted of five daily sessions with a direct current of 1.5 mA for 15 minutes on the F4 or P4 area of the brain at 24-hour intervals.
Results: Significant enhancement of the SWM span as well as a faster response was observed after anodal tDCS in both the anterior and posterior direction. Moreover, stimulation of the left DLPFC induced a faster reaction time compared to the right PPC.
Conclusion: Stimulation DLPFC and PPC, as an element of the frontoparietal network, showed SWM enhancement, with the DLPFC being more affected. Our finding provides new evidence to compare the effect of stimulation on the two main activated cortical areas during visual SWM.
期刊介绍：
BCN is an international multidisciplinary journal that publishes editorials, original full-length research articles, short communications, reviews, methodological papers, commentaries, perspectives and “news and reports” in the broad fields of developmental, molecular, cellular, system, computational, behavioral, cognitive, and clinical neuroscience. No area in the neural related sciences is excluded from consideration, although priority is given to studies that provide applied insights into the functioning of the nervous system. BCN aims to advance our understanding of organization and function of the nervous system in health and disease, thereby improving the diagnosis and treatment of neural-related disorders. Manuscripts submitted to BCN should describe novel results generated by experiments that were guided by clearly defined aims or hypotheses. BCN aims to provide serious ties in interdisciplinary communication, accessibility to a broad readership inside Iran and the region and also in all other international academic sites, effective peer review process, and independence from all possible non-scientific interests. BCN also tries to empower national, regional and international collaborative networks in the field of neuroscience in Iran, Middle East, Central Asia and North Africa and to be the voice of the Iranian and regional neuroscience community in the world of neuroscientists. In this way, the journal encourages submission of editorials, review papers, commentaries, methodological notes and perspectives that address this scope.
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