Ashley M Carter, Bethsabe Romero, Harrison Dai, Simran Phuyal, Danxun Li, Brandon Lucke-Wold
{"title":"Woven Endobridge embolization: Indications and innovation.","authors":"Ashley M Carter, Bethsabe Romero, Harrison Dai, Simran Phuyal, Danxun Li, Brandon Lucke-Wold","doi":"10.36922/an.293","DOIUrl":null,"url":null,"abstract":"<p><p>The treatment of intracranial aneurysms has seen incredible advancements over the last few decades. Long-term occlusion of wide-neck bifurcation aneurysms remains technically challenging. The Woven Endobridge (WEB) embolization device is innovative in its construction and uses. The design of the device has evolved over the last decade. Pre-clinical and clinical trials are ongoing and continue to inform the development of intrasaccular flow-diverting devices. The WEB device is currently approved by the U.S. Food and Drug Administration (FDA) for treating wide-neck aneurysms. The safety and efficacy of the WEB device have yielded promising clinical results that may have additional indications. This review aims to discuss the development of the WEB device and the current state of the WEB device in the treatment of wide-neck aneurysms. We also summarize ongoing clinical studies and potential innovative uses.</p>","PeriodicalId":72072,"journal":{"name":"Advanced neurology","volume":"2 3","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36922/an.293","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/6/13 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The treatment of intracranial aneurysms has seen incredible advancements over the last few decades. Long-term occlusion of wide-neck bifurcation aneurysms remains technically challenging. The Woven Endobridge (WEB) embolization device is innovative in its construction and uses. The design of the device has evolved over the last decade. Pre-clinical and clinical trials are ongoing and continue to inform the development of intrasaccular flow-diverting devices. The WEB device is currently approved by the U.S. Food and Drug Administration (FDA) for treating wide-neck aneurysms. The safety and efficacy of the WEB device have yielded promising clinical results that may have additional indications. This review aims to discuss the development of the WEB device and the current state of the WEB device in the treatment of wide-neck aneurysms. We also summarize ongoing clinical studies and potential innovative uses.
过去几十年来,颅内动脉瘤的治疗取得了令人难以置信的进步。宽颈分叉动脉瘤的长期闭塞在技术上仍具有挑战性。编织内桥(WEB)栓塞装置在构造和用途上都具有创新性。该装置的设计在过去十年中不断发展。临床前和临床试验正在进行中,并将继续为肌内血流分流装置的开发提供信息。WEB 设备目前已获美国食品药品管理局 (FDA) 批准用于治疗宽颈动脉瘤。WEB 装置的安全性和有效性已经取得了令人鼓舞的临床结果,可能会有更多的适应症。本综述旨在讨论 WEB 设备的发展以及 WEB 设备治疗宽颈动脉瘤的现状。我们还总结了正在进行的临床研究和潜在的创新用途。