Prognostic Significance of Preoperative Controlling Nutritional Status Score in Patients Who Underwent Hepatic Resection for Hepatocellular Carcinoma.

Bum-Soo Kim
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Abstract

Malnutrition is common in patients with hepatocellualar carcinoma (HCC), and is associated with postoperative complications after hepatectomy, and also increased mortality. However, there is currently no recommendation for assessment of nutritional status in HCC patients. The controlling nutritional status (CONUT) score has been correlated with prognosis in gastrointestinal cancer patients, but there are few reports on the prognostic significance of the CONUT score in patients who underwent hepatectomy for HCC. Existing results show that patients with high CONUT scores who undergo hepatectomy for HCC have poorer survival outcomes, and experience more complications than other patients. In this paper, we review the literature, and reveal that patients who underwent hepatectomy for HCC with high preoperative CONUT scores had poorer outcomes than those with low CONUT scores. Therefore, we conclude that a preoperative CONUT score may be useful for prognostic prediction in patients with HCC undergoing curative hepatectomy.

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肝癌肝切除术患者术前控制营养状况评分的预后意义。
营养不良在肝细胞癌(HCC)患者中很常见,并与肝切除术后的并发症相关,也增加了死亡率。然而,目前尚无建议评估HCC患者的营养状况。控制性营养状态(CONUT)评分与胃肠道肿瘤患者的预后相关,但CONUT评分在HCC肝切除术患者中的预后意义报道较少。现有研究结果显示,CONUT评分高的HCC患者行肝切除术的生存预后较差,且并发症多于其他患者。在本文中,我们回顾了文献,发现术前CONUT评分高的HCC肝切除术患者的预后比术前CONUT评分低的患者差。因此,我们得出结论,术前CONUT评分可能有助于HCC患者行根治性肝切除术的预后预测。
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