Phlebectomy versus Sclerotherapy in Varicose Vein Patients: A Comparative Study.

Mymensingh medical journal : MMJ Pub Date : 2023-07-01
M P Ahmed, S U Khan, R Hasan, M N Sabah, L N Begum, M S Islam, M Islam
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Abstract

Varicose veins are part of the spectrum of chronic venous disease and include spider telangiectasias, reticular veins, and true varicosities. It may present without advanced signs of chronic venous insufficiency. Sclerotherapy is a treatment choice for patients with varicose veins of lower extremity; it uses the intravenous injection of chemical drugs to achieve the goal of inflammatory occlusion. Phlebectomy, a minimally invasive procedure usually used for higher diameter of varicose veins at the surface of the skin. Objective of the study was to compare the outcome of Phlebectomy and Sclerotherapy in varicose vein patients. It was a quasi experimental study was conducted in the Department of Vascular Surgery in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period of June 2019 to May 2020. Patients admitted with varicose vein and varicosity of the lower limbs with valves and perforator incompetence in the Department of Vascular Surgery, BSMMU, Dhaka, Bangladesh. During this period 60 patients were selected purposive randomly. Patients were divided to 30 patients were treated with Phlebectomy (Group I) 30 patients were treated with Sclerotherapy (Group II). Data were collected according to the pre-designed semi-structured data collection sheet. After editing data analysis were carried out by using the Statistical Package for Social Science (SPSS) version 22.0 Windows software. This study shows average age 40.73±15.50 years in Phlebectomy (Group I) and 38.43±11.08 years in Sclerotherapy (Group II). Males are more commonly involved than females between two groups which was 76.7% in Phlebectomy (Group I) and 70.0% in Sclerotherapy (Group II). The change CEAP improved to 93.3% in patients who underwent phlebectomy when compared to 83.3% in patients who underwent sclerotherapy. During the follow-up with duplex at treated veins showed 93.3% complete occlusion of treated veins in the phlebectomy group, while only 70.0% of the patients in the sclerotherapy group showed evidence of complete occlusion. In phlebectomy group recurrence of leg varicosities were found 6.7% of the patients, while 26.7% of the patients in the sclerotherapy group. The difference was statistically significant between two groups (p=0.038). This study shows phlebectomy to be much better option than sclerotherapy for the treatment of varicose veins and hence can be used routinely. Both phlebectomy and sclerotherapy not only revealed minimal time taken for return to normal activity but also proved to be safer with regard to complications.

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静脉切除术与硬化疗法治疗静脉曲张患者的比较研究。
静脉曲张是慢性静脉疾病的一部分,包括蜘蛛毛细血管扩张、网状静脉和真静脉曲张。它可能没有慢性静脉功能不全的晚期迹象。硬化疗法是下肢静脉曲张患者的一种治疗选择;它是通过静脉注射化学药物来达到炎症闭塞的目的。静脉切除术,一种微创手术,通常用于皮肤表面较大直径的静脉曲张。本研究的目的是比较静脉切除术和硬化疗法治疗静脉曲张的疗效。这是一项准实验研究,于2019年6月至2020年5月在达卡Bangabandhu Sheikh Mujib医科大学(BSMMU)血管外科进行。孟加拉国达卡BSMMU血管外科因静脉曲张和下肢静脉曲张瓣膜和穿支功能不全而入院的患者。在此期间,有目的随机选择60例患者。患者分为静脉切除术组(I组)30例,硬化治疗组(II组)30例。根据预先设计的半结构化数据收集表收集数据。数据编辑后使用SPSS 22.0版Windows软件进行分析。本研究显示,静脉切除术(I组)的平均年龄为40.73±15.50岁,硬化治疗(II组)的平均年龄为38.43±11.08岁。两组患者中男性比女性更常见,其中静脉切除术(I组)为76.7%,硬化治疗(II组)为70.0%,行静脉切除术患者的CEAP变化为93.3%,而硬化治疗患者为83.3%。在随访中,静脉切除术组有93.3%的静脉完全闭塞,而硬化治疗组只有70.0%的患者完全闭塞。静脉切除术组下肢静脉曲张复发率为6.7%,而硬化治疗组为26.7%。两组间差异有统计学意义(p=0.038)。本研究表明静脉切除术比硬化疗法治疗静脉曲张要好得多,因此可以常规使用。静脉切除术和硬化疗法不仅显示恢复正常活动所需的时间最短,而且证明在并发症方面更安全。
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