Antenatal Optimization of Maternal Anemia Leads to Decreased Risks of Maternal Morbidity.

IF 0.7 Q4 OBSTETRICS & GYNECOLOGY Current Obstetrics and Gynecology Reports Pub Date : 2023-06-03 DOI:10.1007/s13669-023-00366-7
Laura A Smith, Brett C Young
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Abstract

Purpose of review: Our review focuses on the appropriate use of intravenous iron to increase the likelihood of achieving target hemoglobin levels prior to delivery to reduce maternal morbidity.

Recent findings: Iron deficiency anemia (IDA) is a leading contributor to severe maternal morbidity and mortality. Prenatal treatment of IDA has been demonstrated to reduce the likelihood of adverse maternal outcomes. Recent investigations of intravenous iron supplementation have demonstrated superior efficacy and high tolerability for the treatment of IDA in the third trimester, compared against oral regimens. However, it is unknown whether this treatment is cost-effective, available to clinicians, or acceptable to patients.

Summary: Intravenous iron is superior to the oral treatment of IDA; however, its use is limited by the lack of implementation data.

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产前优化母亲贫血可降低母亲患病风险。
综述目的:我们的综述侧重于适当使用静脉注射铁,以增加分娩前达到目标血红蛋白水平的可能性,从而降低产妇发病率。最近的研究结果:缺铁性贫血(IDA)是导致严重孕产妇发病率和死亡率的主要因素。IDA的产前治疗已被证明可以降低不良母体结局的可能性。最近对静脉补铁的研究表明,与口服方案相比,在妊娠晚期治疗IDA具有优越的疗效和高耐受性。然而,尚不清楚这种治疗是否具有成本效益,是否可供临床医生使用,或是否可为患者接受。结论:静脉铁治疗IDA优于口服铁;然而,由于缺乏实施数据,它的使用受到限制。
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期刊介绍: This journal aims to provide expert review articles on significant recent developments in obstetrics and gynecology. Presented in clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the diagnosis, treatment, management, and prevention of conditions that compromise the health of women. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endometriosis, infertility, menopause, prenatal medicine, and vulval and cervical lesions. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of nearly 20 international members reviews the annual table of contents, suggests articles of special importance to their country/region, and ensures that topics include emerging research. Commentaries from well-known figures in the field are also provided.
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