Posttraumatic Stress Symptoms Among COVID-19 Survivors After Hospitalization.

IF 2.4 4区医学 Q2 CLINICAL NEUROLOGY Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2023-01-01 Epub Date: 2023-01-30 DOI:10.1176/appi.neuropsych.20220126

Evie Sobczak, Emily P Swafford, Daniel Samano, Danielle Bass, Pardis Ghamasaee, Mohan Kottapally, Amedeo Merenda, Kristine O'Phelan, Jose G Romano, Ralph L Sacco, Tatjana Rundek, Ayham Alkhachroum

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Abstract

Objective: Limited data are available on posttraumatic stress symptoms (PTSS) among COVID-19 survivors. This study aimed to contribute to this knowledge base.

Methods: PTSS among COVID-19 survivors who had been hospitalized were investigated. Patients were identified as COVID-19 positive at hospital admission. COVID-19 survivors were surveyed with the Posttraumatic Stress Disorder Checklist (PCL-5) between March and October 2020 at 5- and 12-month postdischarge follow-up points.

Results: Of 411 patients, 331 (81%) survived to hospital discharge. Of these survivors, 83 (25%) completed the PCL-5 at the 5-month follow-up. Of those patients, 12 (14%) screened positive for PTSS. At the 12-month follow-up, four of eight patients remained PTSS positive. Mean age of follow-up participants was 62±15 years; 47% were women, 65% were White, and 63% were Hispanic. PTSS-positive patients were predominantly non-White (67% vs. 30%, p=0.02), and although the differences were not statistically significant, these patients tended to be younger (56 vs. 63 years, p=0.08) and have shorter intensive care unit stays (2.0 vs. 12.5 days, p=0.06). PTSS-positive and PTSS-negative groups did not differ significantly in prehospitalization neurological diagnoses (11% vs. 8%), psychiatric diagnoses (17% vs. 21%), and intensive care admission status (25% vs. 25%). More patients in the PTSS-positive group had returned to the emergency department (50% vs. 14%, p<0.01) and reported fatigue at follow-up (100% vs. 42%, p<0.001). In the multivariate logistic regression model, non-White race (OR=11, 95% CI=2-91) and returning to the emergency department (OR=19, 95% CI=3-252) were associated with PTSS-positive status.

Conclusion: PTSS were twice as common among hospitalized COVID-19 survivors than among those in the general population.

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COVID-19 幸存者住院后的创伤后应激症状。

目的：有关 COVID-19 幸存者创伤后应激症状（PTSS）的数据有限。本研究旨在为这一知识库做出贡献：方法：对住院治疗的 COVID-19 幸存者的创伤后应激症状进行调查。患者在入院时被确认为 COVID-19 阳性。2020 年 3 月至 10 月期间，在出院后 5 个月和 12 个月的随访点，使用创伤后应激障碍核对表（PCL-5）对 COVID-19 存活者进行了调查：在 411 名患者中，有 331 人（81%）幸存出院。在这些幸存者中，有 83 人（25%）在 5 个月的随访中完成了 PCL-5。在这些患者中，有 12 人（14%）的 PTSS 筛查呈阳性。在 12 个月的随访中，8 名患者中有 4 人的 PTSS 检测结果仍为阳性。随访参与者的平均年龄为 62±15 岁；女性占 47%，白人占 65%，西班牙裔占 63%。PTSS 阳性患者主要为非白人（67% 对 30%，P=0.02），虽然差异无统计学意义，但这些患者往往更年轻（56 岁对 63 岁，P=0.08），重症监护室的住院时间更短（2.0 天对 12.5 天，P=0.06）。PTSS阳性组和PTSS阴性组在入院前神经系统诊断（11%对8%）、精神病诊断（17%对21%）和重症监护入院情况（25%对25%）方面没有显著差异。PTSS阳性组中有更多的患者返回急诊科（50%对14%，P结论：在 COVID-19 的住院幸存者中，PTSS 的发生率是普通人群的两倍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuropsychiatry and Clinical Neurosciences 医学-精神病学

CiteScore

5.30

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： As the official Journal of the American Neuropsychiatric Association, the premier North American organization of clinicians, scientists, and educators specializing in behavioral neurology & neuropsychiatry, neuropsychology, and the clinical neurosciences, the Journal of Neuropsychiatry and Clinical Neurosciences (JNCN) aims to publish works that advance the science of brain-behavior relationships, the care of persons and families affected by neurodevelopmental, acquired neurological, and neurodegenerative conditions, and education and training in behavioral neurology & neuropsychiatry. JNCN publishes peer-reviewed articles on the cognitive, emotional, and behavioral manifestations of neurological conditions, the structural and functional neuroanatomy of idiopathic psychiatric disorders, and the clinical and educational applications and public health implications of scientific advances in these areas. The Journal features systematic reviews and meta-analyses, narrative reviews, original research articles, scholarly considerations of treatment and educational challenges in behavioral neurology & neuropsychiatry, analyses and commentaries on advances and emerging trends in the field, international perspectives on neuropsychiatry, opinions and introspections, case reports that inform on the structural and functional bases of neuropsychiatric conditions, and classic pieces from the field’s rich history.