Anterior Segment Optical Coherence Tomography in Pediatric Ocular Pathology: Imaging Study of 115 eyes.

IF 2.9 3区医学 Q3 ENGINEERING, BIOMEDICAL Expert Review of Medical Devices Pub Date : 2023-07-01 DOI:10.1080/17434440.2023.2223966

Sana Nadeem

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Abstract

Objective: To assess the pediatric anterior segment characteristics in ocular pathology using spectral domain optical coherence tomography (SD-OCT).

Methods: This case series follows 115 eyes of 78 children (2-17 years) with anterior segment pathology in an academic facility. The anterior segment OCT (AS-OCT) analysis was done using the Optopol Revo 80 high-resolution SD-OCT using an imaging adapter. All pathological features visible on imaging were observed, studied, tabulated, and analyzed.

Results: The average age was 11.84 years, with 44 males and 34 females. The primary clinical diagnosis was cataract in 40 (34.8%) eyes, followed by corneal disease in 28 (24.3%) eyes, glaucoma in 18 (15.7%) eyes, and trauma in 15 (13%) eyes. Systemic diseases were associated with 20.9% of the cases. The most common imaging pathology observed was lens opacification in 43 (37.4%), increased reflectivity of the cornea in 31 (28.2%), corneal stromal thinning in 34 (29.6%), increased corneal thickness in 28 (24.3%), a shallow anterior chamber in 17 (14.8%), and cells in the anterior chamber in 18 (15.7%) eyes, along with a multitude of other findings.

Conclusion: This study demonstrates that anterior segment OCT is a useful non-contact technique for the detailed anatomic and pathologic assessment of pediatric ocular diseases.

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前段光学相干断层扫描在儿童眼部病理学中的应用:115只眼的影像学研究。

目的:利用光谱域光学相干断层扫描(SD-OCT)评价儿童眼部前段的病理特征。方法:本病例系列随访了一个学术机构115眼78名儿童(2-17岁)的前节病理。前段OCT (AS-OCT)分析使用Optopol Revo 80高分辨率SD-OCT进行，并使用成像适配器。观察、研究、制表和分析成像上可见的所有病理特征。结果:平均年龄11.84岁，男44例，女34例。临床主要诊断为白内障40眼(34.8%)，其次为角膜病变28眼(24.3%)，青光眼18眼(15.7%)，外伤15眼(13%)。全身性疾病占20.9%。最常见的影像学病理表现为晶状体混浊43例(37.4%)，角膜反射率增加31例(28.2%)，角膜基质变薄34例(29.6%)，角膜厚度增加28例(24.3%)，前房浅17例(14.8%)，前房细胞增生18例(15.7%)，并伴有大量其他表现。结论:本研究表明，前段OCT是一种有用的非接触技术，可用于儿童眼部疾病的详细解剖和病理评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Medical Devices 医学-工程：生物医学

CiteScore

5.90

自引率

3.20%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal serves the device research community by providing a comprehensive body of high-quality information from leading experts, all subject to rigorous peer review. The Expert Review format is specially structured to optimize the value of the information to reader. Comprehensive coverage by each author in a key area of research or clinical practice is augmented by the following sections: Expert commentary - a personal view on the most effective or promising strategies Five-year view - a clear perspective of future prospects within a realistic timescale Key issues - an executive summary cutting to the author''s most critical points In addition to the Review program, each issue also features Medical Device Profiles - objective assessments of specific devices in development or clinical use to help inform clinical practice. There are also Perspectives - overviews highlighting areas of current debate and controversy, together with reports from the conference scene and invited Editorials.