The use of xenogenic dermal matrices in the context of open extremity wounds: where and when to consider?

Nainisha Chintalapudi, Olivia M Rice, Joseph R Hsu
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Abstract

Optimal treatment of orthopaedic extremity trauma includes meticulous care of both bony and soft tissue injuries. Historically, clinical scenarios involving soft tissue defects necessitated the assistance of a plastic surgeon. While their expertise in coverage options and microvascular repair is invaluable, barriers preventing collaboration are common. Acellular dermal matrices represent a promising and versatile tool for orthopaedic trauma surgeons to keep in their toolbox. These biological scaffolds are each unique in how they are used and promote healing. This review explores some commercial products and offers guidance for selection in different clinical scenarios involving traumatic wounds.

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异种真皮基质在四肢开放性伤口中的应用:何时何地考虑?
骨科肢体创伤的最佳治疗包括对骨骼和软组织损伤的精心护理。从历史上看,涉及软组织缺损的临床情况需要整形外科医生的协助。虽然他们在覆盖选择和微血管修复方面的专业知识是无价的,但阻碍合作的障碍是普遍存在的。脱细胞真皮基质是骨科创伤外科医生的一个有前途的多功能工具。这些生物支架在如何使用和促进愈合方面都是独一无二的。这篇综述探讨了一些商业产品,并提供了指导选择在不同的临床情况下涉及创伤性伤口。
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