Durometry for the Assessment of Severity of Post-thrombotic Syndrome and Possible Clinical Applications.

IF 0.7 4区医学 Q4 PERIPHERAL VASCULAR DISEASE Vascular and Endovascular Surgery Pub Date : 2024-01-01 Epub Date: 2023-07-10 DOI:10.1177/15385744231189023

Ana M Salcedo Mercado, Rubén A Rodríguez Cabrero, Rodrigo Lozano Corona, Javier E Anaya-Ayala

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Abstract

Background: Post-thrombotic syndrome (PTS) impacts the patient's quality of life. Available scales to determine its severity remain controversial, therefore, it is of importance to identify new auxiliary methods for the assessment of this sequelae. Measurement of skin hardness (MSH) might be decisive in tracking PTS. The purpose of this study is to assess if the use of durometry is an objective measure to evaluate prognosis of affected limbs in patients with PTS. We compared MSH of extremities with PTS vs healthy limbs, as well as their variation after 3 months of medical treatment to evaluate if durometry can be used to find differences. We strongly believe that measuring and keeping track of skin changes specifically skin hardness can be a useful factor in the prognosis and treatment of PTS.

Methods: Prospective cohort study from January 2021 to February 2022 in patients with unilateral PTS. The MSH of the affected limb was compared to the healthy limb. A calibrated durometer was used, 4 measurements were completed at the time of diagnosis and subsequent follow-up were carried out after 3 months of treatment. The percentage of healing (in case of ulcers) and adherence to treatment was carefully monitored. The statistical program R was used.

Results: A total of 1088 durometric measurements were performed on 17 patients, and 34 limbs. The MSH in limbs with PTS was 39.09 and in the control limbs (19.8) (P = <.00001). After 3 months of treatment, the MSH in PTS varied in PTS limbs (39.09 to 30.4) (P = <.000012). Adherence to treatment was 70.5%.

Conclusions: MSH varied between healthy limbs and the ones with PTS, before and after treatment. Durometry might represent a method for assessing skin changes in patients with PTS.

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硬膜测量法评估血栓形成后综合征的严重程度及其可能的临床应用。

背景:血栓形成后综合征(PTS)影响患者的生活质量。可用的量表来确定其严重程度仍然存在争议，因此，确定新的辅助方法来评估这种后遗症是很重要的。测量皮肤硬度(MSH)可能是跟踪PTS的决定性因素。本研究的目的是评估硬膜测量是否是评估PTS患者患肢预后的客观指标。我们比较了PTS患者与健康肢体的MSH，以及它们在治疗3个月后的变化，以评估是否可以使用硬膜测量法来发现差异。我们坚信，测量和跟踪皮肤的变化，特别是皮肤硬度可以是一个有用的因素，在预后和治疗PTS。方法:从2021年1月至2022年2月对单侧PTS患者进行前瞻性队列研究。比较患肢与健康肢的MSH。使用校准过的硬度计，在诊断时完成4项测量，治疗3个月后进行随访。愈合的百分比(在溃疡的情况下)和坚持治疗被仔细监测。使用统计程序R。结果:共对17例患者，34条肢体进行了1088次硬度测量。PTS患者肢体MSH为39.09，对照组肢体MSH为19.8 (P = P =)。结论:治疗前后，PTS患者与健康肢体的MSH存在差异。硬膜测量法可能是评估PTS患者皮肤变化的一种方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vascular and Endovascular Surgery SURGERY-PERIPHERAL VASCULAR DISEASE

CiteScore

1.70

自引率

11.10%

发文量

132

审稿时长

4-8 weeks

期刊介绍： Vascular and Endovascular Surgery (VES) is a peer-reviewed journal that publishes information to guide vascular specialists in endovascular, surgical, and medical treatment of vascular disease. VES contains original scientific articles on vascular intervention, including new endovascular therapies for peripheral artery, aneurysm, carotid, and venous conditions. This journal is a member of the Committee on Publication Ethics (COPE).