{"title":"The effect of chronic renal failure on survival after nontraumatic lower extremity amputation.","authors":"Salih Beyaz","doi":"10.5152/j.aott.2023.23052","DOIUrl":null,"url":null,"abstract":"The pathophysiology of peripheral neuropathy includes ulcerated lesions resulting from sensory deficits due to vascular occlusion at the microvascular level and foot deformities such as Charcot and osteomyelitis related to these lesions. Microvascular-level pathologies affect the eye, brain, heart, and kidney vessels, causing cataracts, nephropathy, cardiac problems, and mental problems in patients. Diabetes mellitus-related lower extremity circulatory problems develop due to problems in large arteries such as the femoral artery, popliteal artery, and tibial artery. In other words, most patients with DM-related lower extremity circulatory problems have significant renal pathology. In fact, what appears as necrosis, gangrene, and deformity in the lower extremity is the tip of the iceberg.1","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/dd/aott-57-3-124.PMC10544449.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta orthopaedica et traumatologica turcica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5152/j.aott.2023.23052","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
The pathophysiology of peripheral neuropathy includes ulcerated lesions resulting from sensory deficits due to vascular occlusion at the microvascular level and foot deformities such as Charcot and osteomyelitis related to these lesions. Microvascular-level pathologies affect the eye, brain, heart, and kidney vessels, causing cataracts, nephropathy, cardiac problems, and mental problems in patients. Diabetes mellitus-related lower extremity circulatory problems develop due to problems in large arteries such as the femoral artery, popliteal artery, and tibial artery. In other words, most patients with DM-related lower extremity circulatory problems have significant renal pathology. In fact, what appears as necrosis, gangrene, and deformity in the lower extremity is the tip of the iceberg.1
期刊介绍：
Acta Orthopaedica et Traumatologica Turcica (AOTT) is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of the Turkish Association of Orthopaedics and Traumatology, and Turkish Society of Orthopaedics and Traumatology. It is published bimonthly in January, March, May, July, September, and November. The publication language of the journal is English.
The aim of the journal is to publish original studies of the highest scientific and clinical value in orthopedics, traumatology, and related disciplines. The scope of the journal includes but not limited to diagnostic, treatment, and prevention methods related to orthopedics and traumatology. Acta Orthopaedica et Traumatologica Turcica publishes clinical and basic research articles, case reports, personal clinical and technical notes, systematic reviews and meta-analyses and letters to the Editor. Proceedings of scientific meetings are also considered for publication.
The target audience of the journal includes healthcare professionals, physicians, and researchers who are interested or working in orthopedics and traumatology field, and related disciplines.
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