Periconceptional Folic Acid Only Versus Multiple Micronutrients Containing Folic Acid and Association with Gestational Diabetes Mellitus - Beijing Municipality, China, 2017-2021.

Shuangbo Xia, Yushan Du, Ziyang Ren, Jinjuan Zhang, Suhong Gao, Jiamei Wang, Zhiwen Li, Xiaohong Liu, Jufen Liu
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引用次数: 1

Abstract

What is already known about this topic?: Inconsistent results have been reported on the association between periconceptional folic acid only (FAO) or multiple micronutrients containing folic acid (MMFA) supplementation and the risk of gestational diabetes mellitus (GDM) in previous research.

What is added by this report?: In a prospective cohort study conducted among pregnant women in Haidian District, Beijing Municipality, it was observed that those who took MMFA demonstrated a higher likelihood of developing GDM in comparison to those who consumed FAO periconceptionally. Interestingly, the increased risk for GDM in pregnant women supplemented with MMFA compared to FAO was primarily due to changes in fasting plasma glucose.

What are the implications for public health practice?: It is highly recommended that women prioritize the use of FAO in order to yield potential benefits in the prevention of GDM.

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妊娠期仅叶酸与含叶酸的多种微量营养素与妊娠糖尿病的关系——北京市,中国,2017-2021。
关于这个话题我们已经知道了什么?在以往的研究中,关于妊娠期仅补充叶酸(FAO)或补充含有叶酸的多种微量营养素(MMFA)与妊娠糖尿病(GDM)风险之间的关系,报道的结果并不一致。这份报告增加了什么内容?在对北京市海淀区孕妇进行的一项前瞻性队列研究中,观察到服用MMFA的孕妇患GDM的可能性高于孕产期食用FAO的孕妇。有趣的是,与FAO相比,补充MMFA的孕妇患GDM的风险增加主要是由于空腹血糖的变化。这对公共卫生实践有什么影响?强烈建议妇女优先利用粮农组织,以便在预防GDM方面产生潜在效益。
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