Ocular complications of antineoplastic therapies.

IF 2.4 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Future Science OA Pub Date : 2023-08-01 DOI:10.2144/fsoa-2022-0081
Abbas Bader, Madeline Begemann, Ammar Al-Obaidi, Muhammad Hamza Habib, Faiz Anwer, Shahzad Raza
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Abstract

Ocular complications of antineoplastic agents can have a profound effect on the quality of life of cancer patients. New oncologic treatments like monoclonal antibodies, immunotherapies, antibody-drug conjugates, checkpoint inhibitors and growth factor receptors have resulted in increased ocular complications. These ocular complications differs in respect to distinct mechanisms of actions and lead to significant challenges in the management of cancer patients. In this review, we reviewed literature, clinical studies and cases detailing ocular complications due to administration of antineoplastic agents and emphasized the need for communication between oncologists and ophthalmologists toward early detection and management of ocular complications.

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抗肿瘤治疗的眼部并发症。
抗肿瘤药物的眼部并发症对癌症患者的生活质量有着深远的影响。新的肿瘤治疗方法,如单克隆抗体、免疫疗法、抗体-药物偶联物、检查点抑制剂和生长因子受体,导致眼部并发症增加。这些眼部并发症在不同的作用机制方面有所不同,这给癌症患者的治疗带来了重大挑战。在这篇综述中,我们回顾了文献、临床研究和病例,详细介绍了抗肿瘤药物引起的眼部并发症,并强调了肿瘤学家和眼科医生之间沟通的必要性,以早期发现和处理眼部并发症。
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来源期刊
Future Science OA
Future Science OA MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.00
自引率
4.00%
发文量
48
审稿时长
13 weeks
期刊介绍: Future Science OA is an online, open access, peer-reviewed title from the Future Science Group. The journal covers research and discussion related to advances in biotechnology, medicine and health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of research in these fields. All original research articles will be considered that are within the journal''s scope, and have been conducted with scientific rigour and research integrity. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis. Submissions of the following article types will be considered: -Research articles -Preliminary communications -Short communications -Methodologies -Trial design articles -Trial results (including early-phase and negative studies) -Reviews -Perspectives -Commentaries
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