[Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor].

Q3 Medicine Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Pub Date : 2023-01-01 DOI:10.17116/jnevro202312307165

D I Nabiullina, R M Galimova, S N Illarioshkin, I V Buzaev, Sh M Safin, G N Akhmadeeva, N R Mukhamadeeva, D K Krekotin

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Abstract

Objective: To show that effective and safe bilateral MR-guided focused ultrasound (MRgFUS) treatment of essential tremor (ET) is achievable.

Material and methods: Four male patients underwent bilateral thalamotomy. Two patients underwent staged thalamotomy, with the ≥12 month interval between operations. Two patients underwent simultaneous bilateral thalamotomy.

Results: After six months, all patients noted a significant reduction in symptoms on both sides: when assessing tremors with the Clinical Rating Scale for Tremor, the severity of hyperkinesis decreased by 57.5-69.7%. We did not observe any complications in any of the cases.

Conclusion: Our experience indicates that simultaneous bilateral MRI-guided focused ultrasound treatment of ET can be performed safely and effectively. Further research is necessary to estimate the effectiveness and adverse effect rates.

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[核磁共振引导下聚焦超声分阶段同步双侧丘脑切开术治疗特发性震颤的经验]。

目的:探讨双侧磁共振引导聚焦超声(MRgFUS)治疗特发性震颤(ET)的有效性和安全性。材料与方法:4例男性患者行双侧丘脑切开术。2例患者分期行丘脑切开术，手术间隔≥12个月。2例患者同时行双侧丘脑切开术。结果:6个月后，所有患者的双侧症状均显著减轻:当用震颤临床评定量表评估震颤时，运动亢进的严重程度降低了57.5-69.7%。我们没有观察到任何病例的并发症。结论:我们的经验表明，同时双侧mri引导下的聚焦超声治疗ET是安全有效的。需要进一步的研究来评估其有效性和不良反应发生率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Medicine-Psychiatry and Mental Health

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0.80

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0.00%

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