C-reactive protein, D-dimer, erythrocyte sedimentation rate, and troponin in intensive care unit patients with COVID-19 in Iran.

IF 1.5 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Journal of Research in Medical Sciences Pub Date : 2023-01-01 DOI:10.4103/jrms.jrms_352_22
Hassan Salehi, Bahram Pakzad, Marzieh Salehi, Saeed Abbasi, Mohammad Mahdi Salehi, Maryam Kazemi Naeini
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Abstract

Background: The coronavirus disease 2019 (COVID-19) pandemic in Iran has led to a lack of intensive care unit (ICU) facilities. This study examines C-reactive protein (CRP), D-dimer, erythrocyte sedimentation rate (ESR), and troponin in ICU patients with COVID-19 in comparison to COVID-19 patients admitted to the wards in Iran.

Materials and methods: In a case-control study, troponin, CRP, ESR, and D-dimer were compared in the case samples of 109 COVID-19 patients admitted to the ICU, and in the control group, 140 COVID-19 patients admitted to the wards.

Results: The mean of CRP (P < 0.001) and D-dimer (P < 0.001) was higher, whereas troponin (P < 0.001) was lower in patients admitted to the ICU, but no significant difference was observed between the values of ESR (P = 0.292) in the two groups.

Conclusion: This study showed that the values of CRP and D-dimer were higher in patients admitted to the ICU, but no significant difference was observed between the values of ESR in the two groups.

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c反应蛋白、d -二聚体、红细胞沉降率和肌钙蛋白与伊朗重症监护病房COVID-19患者的关系
背景:伊朗2019冠状病毒病(COVID-19)大流行导致重症监护病房(ICU)设施缺乏。本研究检测了伊朗ICU COVID-19患者的c反应蛋白(CRP)、d -二聚体、红细胞沉降率(ESR)和肌钙蛋白,并与住院病房的COVID-19患者进行了比较。材料与方法:采用病例对照研究方法,比较109例ICU收治的病例样本和140例病房收治的COVID-19患者的肌钙蛋白、CRP、ESR、d -二聚体水平。结果:ICU住院患者CRP (P < 0.001)、d -二聚体(P < 0.001)均值较高,肌钙蛋白(P < 0.001)均值较低,但两组ESR值无显著差异(P = 0.292)。结论:本研究显示,ICU住院患者CRP和d -二聚体值较高,但两组ESR值无显著差异。
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来源期刊
Journal of Research in Medical Sciences
Journal of Research in Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
6.20%
发文量
75
审稿时长
3-6 weeks
期刊介绍: Journal of Research in Medical Sciences, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online continuous journal with print on demand compilation of issues published. The journal’s full text is available online at http://www.jmsjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository.
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