Pre-eclampsia and Cardiovascular Disease: From Pregnancy to Postpartum.

IF 3.2 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS European Cardiology Review Pub Date : 2023-06-07 eCollection Date: 2023-01-01 DOI:10.15420/ecr.2022.56
Veronica Giorgione, Matthew Cauldwell, Basky Thilaganathan
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引用次数: 1

Abstract

Hypertensive disorders of pregnancy (HDP) complicate approximately 10% of pregnancies. In addition to multiorgan manifestations related to endothelial dysfunction, HDP confers an increased risk of cardiovascular disease during delivery hospitalisation, such as heart failure, pulmonary oedema, acute MI and cerebrovascular events. However, the cardiovascular legacy of HDP extends beyond birth since these women are significantly more likely to develop cardiovascular risk factors in the immediate postnatal period and major cardiovascular disease in the long term. The main mediator of cardiovascular disease in women with a history of HDP is chronic hypertension, followed by obesity, hypercholesterolaemia and diabetes. Therefore, optimising blood pressure levels from the immediate postpartum period until the first months postnatally could have beneficial effects on the development of hypertension and improve long-term cardiovascular health. Peripartum screening based on maternal demographic, and clinical and echocardiographic data could help clinicians identify women with HDP at highest risk of developing postpartum hypertension who would benefit from targeted primary cardiovascular prevention.

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先兆子痫与心血管疾病:从妊娠到产后。
妊娠期高血压疾病(HDP)使大约10%的妊娠复杂化。除了与内皮功能障碍相关的多器官表现外,HDP还会增加分娩住院期间患心血管疾病的风险,如心力衰竭、肺水肿、急性心肌梗死和脑血管事件。然而,HDP的心血管遗产延伸到出生后,因为这些女性在出生后不久更容易出现心血管风险因素,在长期内更容易患上主要心血管疾病。有HDP病史的女性心血管疾病的主要媒介是慢性高血压,其次是肥胖、高胆固醇血症和糖尿病。因此,从产后立即到产后第一个月,优化血压水平可以对高血压的发展产生有益影响,并改善长期心血管健康。基于产妇人口统计、临床和超声心动图数据的围产期筛查可以帮助临床医生确定HDP妇女患产后高血压的风险最高,这些妇女将受益于有针对性的初级心血管预防。
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来源期刊
European Cardiology Review
European Cardiology Review CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
5.40
自引率
0.00%
发文量
23
审稿时长
12 weeks
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