Treatment of tissue necrosis with hyperbaric oxygen therapy in a patient with pseudomonas endophthalmitis and orbital cellulitis: a case report.

Ismail Uyanik, Husna Topcu, Kubra Serefoglu Cabuk, Ayse Cetin Efe, Mehmet Goksel Ulas
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Abstract

Purpose: This report presents the treatment of tissue necrosis after evisceration with hyperbaric oxygen therapy (HBOT) in a patient with pseudomonas endophthalmitis and orbital cellulitis. Methods: A 49-year-old woman was admitted to our clinic with severe pain and vision loss after cataract surgery 3 days before, and pars plana vitrectomy 2 days before for endophthalmitis, in another hospital. Examination findings included limbal perforation, orbital cellulitis findings, and loss of light perception in the right eye. The patient, who received evisceration surgery and antibiotic treatment, showed loosening of the conjunctival sutures and necrosis in the conjunctiva, tenon, and sclera on the 9th postoperative day. The necrotic tissues were surgically debrided and the patient was referred to HBOT. Results: With HBOT and antibiotherapy, signs of inflammation regressed, healing on the conjunctival surface was accelerated, and prosthesis was suitable for use. Conclusions: Hyperbaric oxygen therapy is a treatment method that plays an active role in the healing of necrotic tissues by increasing the oxygenation and vascularization of the tissue.

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高压氧治疗假单胞菌眼内炎及眼眶蜂窝织炎1例。
目的:报告一例假单胞菌性眼内炎合并眼眶蜂窝织炎患者,采用高压氧治疗术后组织坏死。方法:一名49岁女性于3天前因白内障手术及2天前因眼内炎行玻璃体切除手术后,因严重疼痛及视力下降而入院。检查结果包括角膜缘穿孔,眼窝蜂窝织炎,右眼无光。患者术后第9天出现结膜缝合线松动,结膜、腱、巩膜坏死。手术清除坏死组织,并将患者转介至HBOT。结果:经HBOT联合抗生素治疗,炎症症状消退,结膜表面愈合加快,适合使用假体。结论:高压氧治疗是一种通过增加组织氧合和血管化对坏死组织愈合起积极作用的治疗方法。
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