A surgical resection of hepatic granuloma mimicking intrahepatic cholangiocarcinoma: a case report.

IF 0.5 Q4 ONCOLOGY International Cancer Conference Journal Pub Date : 2023-04-26 eCollection Date: 2023-07-01 DOI:10.1007/s13691-023-00607-9
Kazuki Omachi, Katsunori Imai, Yosuke Nakao, Hiro Nakamura, Takayoshi Kaida, Yuta Shiraishi, Rumi Itoyama, Hidetoshi Nitta, Hiromitsu Hayashi, Tsuguharu Asato, Yoshiki Mikami, Hideo Baba
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Abstract

Hepatic granuloma is relatively rare, and benign tumor of the liver. Herein, we report an unusual case of hepatic granuloma mimicking intrahepatic cholangiocarcinoma (ICC). An 82-year-old woman with a history of viral hepatitis B was admitted for investigation of liver mass in the left lobe. Dynamic computed tomography revealed a mostly hypo-enhancing main tumor with a peripheral ring enhancement, and positron emission tomography demonstrated localized an abnormal accumulation of fludeoxyglucose. Considering the possibility of malignant disease, extended left hepatectomy was performed. The resected tumor was macroscopically a periductal infiltrating nodular type, 4.5 × 3.6 cm in diameter. The pathological findings showed that granuloma and coagulative necrosis were present, and diagnosis of hepatic granuloma was confirmed. Pathological studies demonstrated that periodic acid-Schiff stain, Grocott-Gomori stain and Ziehl-Neelsen stain were all negative in the lesion.

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一例模拟肝内胆管癌的肝肉芽肿的外科切除术。
肝脏肉芽肿是比较罕见的,而且是肝脏的良性肿瘤。在此,我们报告一个不寻常的肝肉芽肿模仿肝内胆管癌(ICC)的病例。一位82岁有乙型病毒性肝炎病史的女性因左叶肝脏肿块入院接受检查。动态计算机断层扫描显示主要肿瘤低增强,周围环增强,正电子发射断层扫描显示局部氟脱氧葡萄糖异常积聚。考虑到恶性疾病的可能性,进行了扩大左肝切除术。切除的肿瘤肉眼可见为导管周围浸润结节型,4.5 × 直径3.6厘米。病理表现为肉芽肿和凝固性坏死,诊断为肝肉芽肿。病理学研究表明,周期性酸性Schiff染色、Grocott-Gomori染色和Ziehl-Neelsen染色均为阴性。
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来源期刊
自引率
14.30%
发文量
57
期刊介绍: This online-only journal publishes original case reports on all types of cancer. In particular, we welcome not only case reports of educational value in the diagnosis and treatment of cancers, but also reports on molecularly analyzed cancer cases, including gene mutations, gene fusions, gene expression, and changes in copy number, regardless of their known clinical significance. Assessing the molecular analysis of a tumor usually requires a “cancer conference” in which experts from various fields discuss it. Even if the authors and their respective “cancer conference” were unable to determine the clinical significance of molecular changes at the time of submission and publication, their data may provide evidence that will help the scientific community develop precision medicine solutions in the future. We welcome case reports with reviews of the literature on similar cases, as they are more useful and valuable to readers than are reports of rare cases. International Cancer Conference Journal is the official publication of the Japan Society of Clinical Oncology (JSCO). - Presents an online-only collection of original case reports on all types of cancer - In particular, welcomes molecularly analyzed cancer cases - The Official Publication of the Japan Society of Clinical Oncology (JSCO)
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