Investigation of 3D-printed PLA–stainless-steel polymeric composite through fused deposition modelling-based additive manufacturing process for biomedical applications

Navin Sakthivel, Jon Bramsch, Phi Voung, Isaac Swink, Saadyah Averick, Hitesh D. Vora
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引用次数: 7

Abstract

Among the several 3D printing technologies, fused deposition modelling (FDM) is gaining popularity because it can fabricate geometrically complex shapes of polymeric bio-implants at reasonable quality and cost mainly due to lower cost of FDM-based 3D printers as well as the filament form of feedstock material. Particularly, to cater the need of cost-effective biomedical applications, both poly(lactic) acid (PLA) and stainless-steel materials individually displayed the biocompatibility for various biomedical applications. The pure polymeric components are generally lower in mechanical strength, but these limitations can be resolved by developing a polymer–metallic composite; therefore, the recently developed PLA–stainless-steel composite was selected for the present work. This is new material and the current literature lacks in providing the necessary FDM processing parameters to obtain desired functional properties of PLA–stainless-steel components with unaltered biocompatibility. Therefore, the objective here is to obtain the optimized processing parameters through the design of experiments that shows the desired functional properties of PLA–stainless-steel specimens manufactured by FDM and later validate the structural strength through the tensile and impact tests. It was observed that the PLA–stainless-steel composite has a toughness of 18 kJ/m2 and has an ultimate tensile strength of ~69 MPa at 45° and ~23 MPa at 90° raster orientation of the print. Biocompatibility of the PLA–stainless-steel polymeric composite was assessed using pre-osteoblast cells, and materials were found to have biocompatibility unchanged from pure PLA. Overall, it was proved from this work that the low-cost desktop FDM printer can be numerically optimized using statistical analyses to fabricate the next-generation biomaterials for biomedical implants with tailored dimensions and surface finish with required mechanical strength and biocompatibility.

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基于熔融沉积建模的3d打印pla -不锈钢聚合物复合材料生物医学应用研究
在几种3D打印技术中,熔融沉积建模(FDM)越来越受欢迎,因为它可以以合理的质量和成本制造几何形状复杂的聚合物生物植入物,这主要是由于基于FDM的3D打印机成本较低以及原料的长丝形式。特别是,为了满足成本效益高的生物医学应用的需要,聚乳酸(PLA)和不锈钢材料分别显示了各种生物医学应用的生物相容性。纯聚合物组分的机械强度通常较低,但这些限制可以通过开发聚合物金属复合材料来解决;因此,本文选择了新开发的pla -不锈钢复合材料。这是一种新材料,目前的文献缺乏提供必要的FDM加工参数,以获得具有不变生物相容性的pla -不锈钢部件所需的功能特性。因此,本文的目标是通过实验设计获得优化的工艺参数,以显示FDM制造的pla -不锈钢试样所需的功能性能,然后通过拉伸和冲击试验验证结构强度。结果表明,pla -不锈钢复合材料的韧性为18 kJ/m2,在45°和90°光栅方向的拉伸强度分别为~69 MPa和~23 MPa。使用成骨前细胞评估PLA -不锈钢聚合物复合材料的生物相容性,发现材料具有与纯PLA相同的生物相容性。总的来说,这项工作证明了低成本桌面FDM打印机可以通过统计分析进行数值优化,以制造具有定制尺寸和表面光洁度的下一代生物医学植入物生物材料,并具有所需的机械强度和生物相容性。
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