[ABCD-10 scale as a predict of mortality in children with severe pharmacodermias. Case report].

Q3 Medicine Revista alergia Mexico Pub Date : 2023-05-24 DOI:10.29262/ram.v70i1.1069

Britza Barrios-Díaz, Ana Paola Macías-Robles, Héctor Hugo Campos-Téllez, Rosa María Cortés-Grimaldo, Hilda Lilian Carvajal-Alonso, Kareli Guadalupe Coronado-Hernández, Carlos David Estrada-García, Adriana Ramírez-Nepomuceno, Marlén Barreto-Alcalá, David Esparza-Amay

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引用次数: 1

Abstract

Background: The severe pharmacodermias (SF) are associated with high morbidity and mortality. Chronic kidney failure (CKD) related with dialysis is one of the main factors associated with higher mortality. ABCD-10 is a predictive mortality scale that includes the history of dialysis.

Case report: Male 2 years old with a history of CKD on peritoneal dialysis and Lennox-Gastaut syndrome, admitted to the hospital due to acute peritonitis and developed SJS-NET secondary to phenytoin administration. He was treated with immunoglobulin and systemic steroid without improvement. Septic shock was added, presenting a fatal outcome.

Conclusions: In the case presented, the ABCD-10 scale was applied, reporting a greater prediction of mortality compared to SCORTEN due to a history of dialysis. In children with SF there are no validated predictive mortality. Future initiatives should search for risk factors for mortality in children who develop SF for the creation of a predictive mortality scale.

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[ABCD-10量表用于预测严重药皮病患儿的死亡率。]病例报告)。

背景:严重药皮病(SF)具有较高的发病率和死亡率。与透析相关的慢性肾衰竭(CKD)是导致高死亡率的主要因素之一。ABCD-10是一种包括透析史的预测死亡率量表。病例报告:男性，2岁，腹膜透析CKD病史，lenox - gastaut综合征，因急性腹膜炎入院，苯妥英致继发SJS-NET。经免疫球蛋白和全身类固醇治疗无好转。脓毒性休克，导致死亡。结论:本病例采用ABCD-10量表，与有透析史的SCORTEN相比，ABCD-10量表对死亡率的预测更高。SF患儿没有有效的预测死亡率。未来的举措应寻找SF儿童死亡率的危险因素，以创建预测死亡率量表。

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